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Polycystic Ovaries

Role of environmental estrogens in deterioration of male fertility – (01-18-03)

February 16, 2014 by James Bogash

Role of environmental estrogens in deterioration of male fertility

Fertility is actually becoming quite big business in Western medicine and more and more of an issue with patients. If a woman is not fertile, their is something with their physiology that is imbalanced–estrogen dominance, polycystic ovaries, anovulation–that needs to be addressed. The medical approach of forcing ovulation on a system that is NOT ovulating because it is not ready for it just stumps me. Fix the menstrual cycle and fertility should return. I had a friend with poor lifestyle habits, including smoking. She had seen fertility doctors and was contemplating treatment. She finally quit smoking and was pregnant in weeks. With male fertility, external influences seem to be a major player–here we seen xenoestrogens affecting fertility. Want scary? Studies in mice has shown reduction in male fertility 3 generations later when zinc was deficient.

ScienceDirect – Fertility and Sterility: Role of environmental estrogens in the deterioration of male factor fertility

Read entire article here

Filed Under: Healthy Pregnancy and Women's Health Tagged With: environmental estrogens, male fertility, Polycystic Ovaries, xenoestrogens

Impaired Carotid Viscoelastic Properties with Polycystic Ovaries – (07-08-02)

May 26, 2013 by James Bogash

Impaired Carotid Viscoelastic Properties with Polycystic Ovaries

The picture of insulin resistance, polycystic ovaries, and cardiovascular disease gets clearer with each research paper. Insulin affects conversion of testesterone to estrogen via 15,20 lyase and aromatase enzymes, leading to increased levels of testesterone. The increased testosterone strongly predisposes to PCOS. On the vascular side of the picture, insulin has been shown to reduce to “stretchiness” of arteries. Here we see A=B, B=C, with research to support A=C.

Circulation — Abstracts: Lakhani et al. 106 (1): 81

Read entire article here

Filed Under: Heart Disease, Hormone Tagged With: cardiovascular disease, Carotid Viscoelastic, Polycystic Ovaries, testesterone

INFERTILITY AND PCOS: OVARIAN DRILLING VS METFORMIN – (10-20-04)

October 21, 2012 by James Bogash

Metformin Administration Versus Laparoscopic Ovarian Diathermy in Clomiphene Citrate-Resistant Women with Polycystic Ovary Syndrome

Am I missing something here? The relationship between polycystic ovaries and metabolic syndrome is beyond reproach. Lifestyle changes to manage metabolic syndrome is the first (and, in my opinion, only) line of defense and has proven incredibly effective to eliminate insulin resistance. The few docs aware of the relationship have used metformin successfully as well, but it is not my choice. So why, why, why do we continue to have procedures like ovarian drilling and laproscopic diathermy for PCOS???? I’m not a woman and thus don’t have ovaries to deal with, but I could pretty much guess that, if I was, I would prefer not to have my reproductive organ drilled when lifestyle changes and exercise are MORE effective!! If anyone has an answer for this one, please forward it to me…

Metformin Administration Versus Laparoscopic Ovarian Diathermy in Clomiphene Citrate-Resistant Women with Polycystic Ovary Syndrome.

Read entire article here

Filed Under: Insulin, Ovarian Hormones Tagged With: diathermy, Laparoscopic, metabolic syndrome, Metformin, PCOS, Polycystic Ovaries

LINK BETWEEN INSULIN RESISTANCE AND PCOS – (06-20-05)

July 8, 2012 by James Bogash

Changes in Glucose Tolerance over Time in Women with Polycystic Ovaries

The research pointing to the link between insulin resistance and PCOS is very, very strong.  And yet I read an article in a pregnancy/mother magazine about PCOS.  The last therapy mentioned was managing insulin resistance.  While I was exuberant that it was mentioned at all, why last?  This should absolutely, unquestionably be the first line therapy.  If infertility associated with PCOS is treated with fertility drugs, then the doctor just missed the true problem of insulin resistance and should be liable for malpractice.

Quite frankly, I am sick of patients coming through my office that have a glowing light above their head flashing “insulin resistant” and yet, despite multiple providers that they see, no one has addressed the insulin resistance.  Their is no longer any excuse not the know this.  Any physician in clinical practice today that does not fully understand the negative ramifications of insulin resistance on their patients should be kicked out of medicine.  Period.

Read entire article here

Filed Under: Healthy Pregnancy and Women's Health, Insulin Tagged With: insulin resistance, PCOS, Polycystic Ovaries

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