LifeCare Chiropractic

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Atherosclerotic

Six-Year Effect of Vit C, E on Atherosclerotic Progression – (03-04-03)

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Six-Year Effect of Vit C, E on Atherosclerotic Progression.

Whenever a study comes out showing no benefit of antioxidants on progression/prevention of CVD, one has to look at the totality of the evidence. The evidence (not to mention that it makes sense from a physiology/pathology standpoint) is quite plentiful that antioxidants protect against CVD.

Circulation — Abstracts: Salonen et al. 107 (7): 947

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Physically Fit Children Have Lower Plasma Fibrinogen – (09-11-00)

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Physically Fit Children Have Lower Plasma Fibrinogen

Just another reason why activity is important at all ages. Remember that fibrinogen is being more and more recognized for its role in heart disease. This researcher hits the nail on the head with a sledgehammer as squarely as you possibly can with his last quote…

Am J Epidemiol 2000;152:212-218 There is an inverse relationship between plasma fibrinogen levels and physical fitness in children, according to findings from the Columbia University BioMarkers Study. As Dr. Shea explained, “The role of cardiovascular protective factors in childhood is not well known. We would like to understand it better because we would like to prevent the process of atherosclerosis rather than trying to reverse it later in life when it becomes clinically apparent.” “The dream,” he concluded, “is for real primary prevention of the atherosclerotic process itself, beginning in childhood.”

Effective and Safe Modification of Multiple Atherosclerotic Risk Factors – (02-12-01)

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Effective and Safe Modification of Multiple Atherosclerotic Risk Factors

This article looks at the lowering of multiple risk factor for atherosclerosis simultaneously. As far as I’m concerned, this is the ONLY way to address this problem. Of interesting note in this study was the use of niacin, 500mg twice daily (a very reasonable dose) to raise HDL levels 30%. Add some exercise and avoidance of saturated fat and your LDL/HDL ratios will be looking pretty good!!

Am Heart J 140(5):792-803, 2000 Patients with peripheral arterial disease (PAD) are at an increased risk of cardiovascular mortality and morbidity and thus are an excellent group in whom to evaluate the feasibility and the effect of an aggressive multifactorial intervention on atherosclerotic vascular disease risk factors. The Arterial Disease Multiple Intervention Trial (ADMIT) was designed to determine the efficacy, safety, and compliance of an multifactorial therapy on selected atherosclerotic disease risk factors in patients with PAD. Niacin increased HDL cholesterol levels by 30%, with the majority of effect achieved at a dosage of 500 mg twice daily. Warfarin had an anticoagulant effect. The antioxidant vitamins resulted in a significant increase in vitamin E, C, and beta-carotene plasma levels. Overall, compliance was high and few adverse effects were reported. ADMIT demonstrates that it is both feasible and safe to modify multiple atherosclerotic disease risk factors effectively with intensive combination therapy in patients with PAD.