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Arthritis

MELATONIN-CYTOKINE MAY CAUSE RHEUMATOID ARTHRITIS – (07-25-05)

July 8, 2012 by James Bogash

The melatonin-cytokine connection in rheumatoid arthritis

I must say that this one caught my eye.  There has been much research lately into how much melatonin protects the brain from oxidative stress, but like any natural compound, there is a potential downside.  Melatonin has an ability to up-regulate the immune system.  While this may be a good thing for someone with a suppressed immune system, it may be a bad thing for someone with a Th1 dominated autoimmune condition–in this article rheumatoid arthritis.

I know that I, for one, will no longer recommend melatonin if there is any concern for autoimmune conditions.  Interesting to note, though, is the vit D, sunlight and melatonin connection.  Sunlight suppresses melatonin production and stimulates vit D production.  Might this interaction somewhere play a role as well?  Picture today’s typical office job–indoors most of the day with little vit D production (which is known to protect against some autoimmune disorders) and maybe elevated melatonin levels at inappropriate times of the day.  This may be a recipe for disaster.

Read entire article here

Filed Under: Arthritis, Autoimmunity, Oxidative Stress Tagged With: arthritis, melatonin-cytokine, oxidative stress, rheumatoid arthritis, Strengthen your immune system, Vit D

CARTILAGE BREAKDOWN A MARKER FOR OSTEOARTHRITIS PROGRESSION – (04-10-06)

July 1, 2012 by James Bogash

Molecular markers of cartilage breakdown and synovitis at baseline as predictors of structural progression of hip osteoarthritis

This study evaluated the use of markers of cartilage breakdown as marker for osteoarthritis progression.

The markers used were effective, but I would like to see this same type of study done on natural approaches such as glucosamine and chondroitin instead of instead of an anti-inflammatory compound like diacerein. Granted, diacerein does not inhibit the metabolism of chondrocytes like other NSAIDs, but we all know my bent towards natural compounds..

Read entire article here

Filed Under: Arthritis Tagged With: chondroitin, diacerein, glucosamine, NSAIDs dangerous, osteoarthritis

PAINFUL COMBINATION – STATINS FOR CHOLESTEROL AND ARTHRITIS

May 3, 2012 by James Bogash

I just left a meeting where I found out one of our members had been hospitalized for kidney failure following rhabdomyolysis (muscle damage).  The first thought to pop into my mind was statins.  This may or not have been the case, but it is a well known association with taking statins to lower cholesterol.

Since their introduction, the statin class of drugs (think Lipitor, Crestor) has been on a pedestal.  By 2003, Lipitor was the best selling drug in history.  Just like every drug, the statin class of drugs has a dark side and contributes to conditions such as muscle damage, heart damage, liver and kidney problems, diabetes and cancer.

The sad part about all this is that basically, statins absolutely suck at preventing a first heart attack (the data is somewhat better for 2nd heart attacks, but still trumped by dark chocolate…).  There is no other way to describe it.  I have review the absolute effectiveness of statins in previous posts.  Compare this to the effects of natural approaches:

  1. Nuts to lower cholesterol
  2. Berries to improve and protect your heart
  3. Honey helps to protect the heart

The bottom line is that statins are a very ineffective at preventing a first heart attack (overall, lowers absolute risk of having  a heart attack about 1%, the risk of dying from a heart attack even less) and there are natural approaches that are much more effective and safer and cheaper.  Worse, there are side effects that are high prevelant and occasionally life threatening.

However, if none of the above side effects really concern you, here’s a new one to add:  Damaging rheumatoid arthritis.

In this particular study, researchers found a strong association (absolute 7.3% increase–that means an extra 7 cases of RA for every 100 patients treated with statins) between statin use and rheumatoid arthritis.  Keep in mind that RA is one of the most debilitating forms of arthritis. 

All because of the use of a drug that will make your numbers look better, but don’t actually fix anything.  Lifestyle is the ONLY thing that can do that.

Filed Under: Arthritis, Cholesterol Tagged With: cholesterol, rheumatoid arthritis, statin

GET RID OF OSTEOARTHRITIS WITH SOFT TISSUE APPROACHES – (12-03-07)

April 21, 2012 by James Bogash

Chondroitin for Osteoarthritis of the Knee or Hip

This review found minimal or no benefit to the use of chondroitin for arthritis of the knee. Before we jump to conclusions… How many people in these studies with knee/hip pain was actually coming from the joint itself? The answer, of course, is that we don’t know. Degenerative joint disease = pain in clinical studies but that just isn’t always true.

For a physician that addresses soft-tissue components of injuries, how often does a knee loaded with arthritis get complete relief with some solid soft tissue approaches? I can personally say that aggressive soft tissue techniques like Graston can sometimes bring complete relief for many OA sufferers. Did we fix the OA? Of course not–but in these cases the soft tissues were the primary pain generators. So we could assume that any type of joint support would not be effective in these cases.

So, in these studies, did they rule out non-joint related pain generators? More of a rhetorical question because of course they did not.

Read entire article here

Filed Under: Arthritis, Knee Pain Tagged With: arthritis, Graston techniques, Hip, knee, osteoarthritis

RECIPE TO CREATE A DRUG USER

April 2, 2012 by James Bogash

The Federal Bureau of Narcotics was formed over 80 years ago in 1930.  In 1954, President Eisenhower formed a council to battle narcotics use here in the United States.  In 1971 President Nixon coined the term “war on drugs.”  This was further strengthened by President Reagan in 1982.  Overall, untold billions of federal dollars have been spent on this effort.  Man did we get it all wrong.

We were spending our money and efforts at illicit drug use, while slowly building a society that not only condoned prescription narcotic drug use, but PAID FOR IT!  Beginning at least in 2008, the number of deaths associated with prescription narcotic use exceeded those deaths caused by illicit drug use.

Codeine, OxyContin, Percocet, Vicodin, morphine,  Xanax and Valium (these 2 are benzodiazapines–but frequently abused), Valium, Tramadol, Tylenol 3.

It never ceases to amaze me how quickly prescriptions for narcotic pain relievers are given out.  In the ER it is almost a given.  High likelihood in urgent care.  Still far too common in a primary care settings.

And then there are the non-steroidal anti-inflammatory drugs (NSAIDs).  Why should we throw something as safe and harmless as NSAIDs in with the narcotic drugs?

I firmly believe that, as time progresses (decades, probably) we will begin to understand just how dangerous this class of drugs is.  Arthritis /  joint damage, heart attacks, strokes, impotence, GI bleeds, disruption of intestinal barriers, dementia…this list of known effects seems to lengthen every month.

The problem here is that of sheer scale of use. Between over the counter use and the 70 Million prescriptions per year, it is estimated that there are 30 BILLION doses used per year.  That’s with a “b.”  Even uncommon side effects become magnified by this volume of use.  Of course, bleeding ulcers, heart attacks and strokes are not uncommon, so the math just gets more complicated from there.

So what does all of this have to do with this particular article?  This article looked at analgesic use after low risk surgery (gall bladder, cataract, TURP for prostate enlargement and varicose vein stripping) and what happens after 7 days and one year.  The results were surprising:

  1. Opioids were newly prescribed to 7.1% within 7 days of being discharged from the hospital
  2. Opioids were prescribed to 7.7% at 1 year from surgery
  3. Instead of going down, the number of patients receiving a prescription for opioids at 1 year increased to 15.9%
  4. Overall, an opioid prescriptions within 7 days of surgery made it  44% more likely to be a long term user
  5.  NSAIDs were prescribed to 0.3% within 7 days of discharge
  6. NSAIDs prescriptions jumped to 7.8% at 1 year from surgery
  7. Those taking NSAIDs within 7 days of surgery were almost 400% more likely to become long-term NSAID users

Wow.  Talked about generating a society that is addicted to drugs.  And while this study looks at low risk surgery, how similar would the numbers be for neck pain?  Low back pain?  Knee pain or headache?  Makes me happy to be a chiropractor.

Again, I would ask…is the “War on Drugs” looking at the wrong side of the prescription pad?

Filed Under: Arthritis, Chiropractic Care, Knee Pain, Low Back Pain, Neck Pain, NSAIDs Dangerous Tagged With: ibuprofen, natural pain relief, NSAIDs dangerous, opioids

TONING UP OR DOWN THE ENTIRE BODY’S IMMUNE RESPONSE – (01-15-07)

March 20, 2012 by James Bogash

The gut-joint axis: cross reactive food antibodies in rheumatoid arthritis

While the research has supported this for some time, clinicians have been slow to catch up.  Bottom line is that the GI tract has a strong ability to tone up or tone down the entire body’s immune response.  Insult the GI tract too much with food allergies and a signal will go out to the rest of the body that we’re under attack, raising our overall defense and increasing likelihood of our body mistakenly attacking our own cells.  An elimination diet is absolutely essential for anyone with an autoimmune disease.

Additionally, our view of autoimmune disorders is changing.  While we have always viewed AI conditions as dysfunctions of the immune system that need to be surpressed, evidence is increasing that the immune system is actually doing what it’s supposed to be doing, but that the tissues themselves (DNA in Lupus, myelin sheat in MS, Type II collagen in RA…) are being excessively damaged.  This is what needs to be fixed, not the immune system.

Read entire article here

Filed Under: Arthritis, Food Allergy Tagged With: autoimmune disorders, gut-joint axis, Lupus, rheumatoid arthritis

PULLED A MUSCLE? WHY POPPING THAT ALEIVE IS A VERY BAD IDEA

March 3, 2012 by James Bogash

Obviously, this article is going to sound a little self serving since I am, after all, a chiropractor in Mesa with a vested interest in my patients not taking drugs of any kind unless absolutely necessary. My more inquisitive patients all seem to ask a similar question…if the body is so brilliantly designed, where do chronic musculoskeletal complaints come from?

Certainly there are injuries that are severe and result in tissue damage that is much greater in degree and have a high likelihood of producing chronic pain. Think skiing, skateboarding or snowboarding injury. High speed car crashes. Motorcycle accidents. Equestrian wipeouts. Surgery.

But what about the weekend warrior who pulls a hamstring? The 8 hour per day computer user? Or me, as a lifelong martial artist, who has had untold injuries over the decades to pretty much every potential area of my body? Why do these situations lead to chronic pain?

My personal thought (backed by lots of research and years of clinical practice) is that the development of chronicity has much to do with how we handle the immediate period after the injury or onset of symptoms. What do the vast majority of us do (which is, of course, the direction indicated by billions of dollars of advertising) in this immediate period? Rest the area and pop an over the counter pain medication or anti-inflammatory. This is arguably the worst possible combination possible.

Why?

First, let’s address the immobilization aspect. Literally within minutes of immobilization, the soft tissues surrounding the immobilized joint begin to break down. The longer that joint is kept from a full range of motion, the worse the tissue damage. Anyone who’s ever broken a bone and had it casted can attest to how much joint motion is lost once the cast comes off. Recovery time can be even longer than the immobilization time.

With tissue injury, ultimately, the size of the region affected is larger than the original injury size. Consider the swelling associated with an ankle sprain—the area of the ligament injury may actually be very small, but the entire ankle, foot and lower leg swells up to the size of a balloon and becomes discolored. Now the amount of injured tissue is much larger than the original injury and this tissue has to heal. But healing occurs in a haphazard fashion if the area is not used. I give the analogy of a leak in your bathroom faucet. You call in the plumber. He shows up with a crew that’s been drinking at the bar for half the day. They proceed to rip out half the bathroom to fix the leak and rebuild with a level of skill only a three-sheets-to-the-wind Irishman can achieve.

Our body is no different. As we heal after an injury, the new tissue, whether it is bone, muscle, ligaments, fascia or tendons, is laid down in a disorganized manner. Only as that region goes through movement do these healing tissues become stressed and become organized along the lines of force. Immobilization becomes the enemy of proper healing.

Next, let’s address the routine use of over the counter anti-inflammatories, or prescription, for that matter. All anti-inflammatory medications are, by their very nature, designed to interfere with the inflammatory process. Unfortunately, inflammation is the normal process of healing. Disrupt this and you disrupt the ability of our tissues to heal the way they were designed. Contrast this with the use of ice right after an injury. Ice works simply by reducing blood flow to the newly injured area, thus keeping the damage of the drunken plumbing crew from getting too out of hand. Arguably a good idea. But then blocking the crew from repairing the area in specific ways, like maybe taking all their crescent wrenches away from them, is going to result in improper repair.

Hopefully you can begin to understand why the combination of immobilization and anti-inflammatory medications immediately after an injury may be the first step in developing chronic pain. Repeat this cycle the next time you injure the area and the dysfunction begins to mount.

This particular study demonstrates just how bad the outcome can be when non-steroidal anti-inflammatories (NSAIDs) are used after a rotator cuff surgery tendon repair. Researchers looked at the tendon to bone healing that occurred in the presence of NSAIDs and found that every case was affected, from complete failure of healing to weakened tissue. No normal healing tissue was present when compared to the group in which no NSAIDs were used.

While this relates to surgical cases in animals, the same process is interfered with in every case of tissue injury that happens in our body when NSAIDs are used. While my opinion that you should run to your chiropractor at the first hint of any type of pain may sound self-serving, the reality is that you may be diverting the development of chronic pain.

Filed Under: Arthritis, Chiropractic Care, Knee Pain, Low Back Pain, Neck Pain, NSAIDs Dangerous Tagged With: anti-inflammatories, chiropractic, chronic pain, NSAIDs dangerous, pain

HOW DO WE SAVE MASS AMOUNTS OF MONEY FOR MEDICARE??

January 30, 2012 by James Bogash

HOW DO WE SAVE MASS AMOUNTS OF MONEY FOR MEDICARE??  We make sure that the surgeries we do on seniors with lumbar spine arthritis are not merely to make money for the surgeons.

In a study spanning 5 years on seniors with lumbar spinal stenosis (an advanced degenerative condition of the lumbar spine), the number of complex (multilevel) fusions went up FIFTEEN times!! Sounds great if this was a better surgery than a simpler one, but unfortunately this is not even close–there was triple the risk of life threatening complications with the complex fusion.  The price tag for this fiasco?  $50,000 more for the complex surgery.  Wow.

Good thing they need to hammer down on chiropractic claims.  Wouldn’t want some evil chiropractor to rip Medicare off for $250…especially since our office uses Flexion Distraction which can be very successful for treatment of stenosis.

Read entire article here

Filed Under: Arthritis, Chiropractic Care Tagged With: arthritis, flexion distraction, lumbar spinal stenosis

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