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by James Bogash
Watermelon Increases Concentrations of Lycopene, beta-Carotene
What more could we ask for? Personally I could eat watermelon 24 hours a day. Recall that lycopene has strong evidence supporting its use for prevention and treatment of prostate cancer and is also present in tomato and grapefruit.
nutrition.org — Abstracts: Edwards et al. 133 (4): 1043
by James Bogash
Saw Palmetto for Prostate Disorders.
American Family Physician has been putting out some nice articles on natural products that are fair and well-balanced. Here we see further support for the use of saw palmetto for prostate enlargement. I would add to this mix lycopene (the red carotenoid that gives tomatos and watermelo their color) and cruciferous veggies (see below…) for further prostate health.
Saw Palmetto for Prostate Disorders – March 15, 2003 – American Family Physician.
by James Bogash
Dietary Antioxidants Do Not Reduce Carotid Atherosclerosis Risk
When I first read this title I was a little surprised. Strangely enough, when I went to the original journal article, the findings show that antioxidants do protect against atherosclerosis, namely dietary Vit E and lycopene. The effect was not great, but these nutrients are only one small part of a program towards good cardiovascular health. The other antioxidants studied (Vit A, C and beta-carotene) did not show an effect. How could a major reporting agency come up with the title shown above when the results are clearly the opposite. The bias here almost sickens me.
by James Bogash
Reduction of exercise-induced asthma oxidative stress by lycopene
Lycopene is an antioxidant found in red fruits such as tomatoes and watermelon. Lycopene is the substance in tomatoes that recent evidence suggests may protect against heart disease and prostate cancer. This study uses an extract containing high levels of lycopene. Remember that the whole food will contain numerous other substances that may very likely increase the effectiveness of the lycopene.
Synergy Abstract
by James Bogash
Resveratrol Enhances Differentiation Induced by Butyrate
This study on colon cancer cells shows an additive effect of resveratrol (found in red wine and peanuts) and butyrate (a short chain fatty acid formed by bacteria acting on soluble fiber in the gut). With studies like this, we start to see why certain traditional diets have the health -promoting effects they have. The Mediterranean diet has already show to be beneficial via increased absorption of lycopene (fat soluble carotenoid) with olive oil intake. This research study mechanism would find lower rates of colon cancer in patients combining wine intake with whole grains.
Nutrition.org — Abstracts: Wolter and Stein 132 (7): 2082
by James Bogash
Lycopene Helps Fight Infertility in Men
Given that lycopene (a substance found in many red fruits and veggies such as tomatoes and watermelon) has been shown to lower risk of prostate cancer, it is not surprising that this substance also has an effect on other male reproductive issues. Combine lycopene with zinc and therapies designed to restore hormone levels and many cases of infertility may be resolved.
(article) Lycopene, an antioxidant found in watermelon, grapes, tomatoes and some shellfish, seems to treat infertility in men, studies conducted at the All India Institute of Medical Sciences (AIIMS) in New Delhi show. AIIMS researchers Dr. Rajeev Kumar and Dr. N. P. Gupta had 30 infertile male patients, ages 23 to 45, take 2 mg oral lycopene twice daily for 3 months. “Lycopene is one of the 650 carotenoids found in high concentrations in male testes and lower levels of lycopene are found in infertile males,” Dr. Gupta told Reuters Health. The duration of infertility in these men had ranged from 1.2 to 20 years, according to the researchers. In all cases, infertility was idiopathic. Twenty-seven patients had oligospermia, 26 had impaired sperm motility and 22 had abnormal sperm morphology. All three parameters were found in 14 patients, another 14 had two abnormal parameters and the remaining two patients had a single abnormality. After lycopene had been administered for 3 months, sperm concentration improved in 67% of the 30 patients. Maximum improvement was noted in patients with baseline sperm concentrations greater than 5 million/mL. Overall, 73% patients showed improved sperm motility and 63% showed improvement in sperm morphology. “We found that improvement in sperm concentration and motility was statistically significant,” Dr. Gupta said in the interview with Reuters Health. There were six pregnancies after the trial, he added. “Oral lycopene therapy does seem to have a positive role in the management of infertility of unknown causes,” Dr. Gupta concluded. “However, larger randomized controlled trials are essential before definitive therapeutic guidelines can be laid down.”
by James Bogash
Formulation Provides Lycopene with Same Bioavailability as Tomato Paste
Speaking of the carotenoids… This article is trying to find better ways to increase the absorption of the fat soluble lycopene. Without going to great lengths found in this article, one of the ways that researchers believe the Mediterranean diet provides extensive health benefits is the combination of olive oil with tomatoes, thus increasing the bioavailability of the lycopene.
Nutrition.org — Abstracts: Richelle et al. 132 (3): 404
by James Bogash
Prevalence of Prostate Cancer among Men with a PSA Equal or less than 4.0 ng/ml
Remember studies like this when the American Cancer Society puts out their propaganda about “prevention” of prostate cancer by getting your PSA levels checked. THIS IS ABSOLUTELY, 100% NOT PREVENTION!! And this study proves it yet again. The PSA levels in 15% patients with prostate cancer in this study were normal. To me, this means that the PSA is not effective in identifying prostate cancer.
Now, I do feel it can be used as a baseline that can then be checked in subsequent years for changes. In summary–prevention via good diet, lots of lycopene containing fruits, high intakes of cruciferous veggies to modulate the breakdown of estrogen (yes..I said estrogen) and maintenance of a healthy body weight.
NEJM — Prevalence of Prostate Cancer among Men with a Prostate-Specific Antigen Level <=4.0 ng per Milliliter –
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