LifeCare Chiropractic

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Lipid Metabolism

Chromium Picolinate Improves Carbohydrate and Lipid Metabolism – (06-06-02)

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Chromium Picolinate Improves Carbohydrate and Lipid Metabolism

Chromium is one of the mainstays for use in insulin disorders because it is believed to help insulin due its job. This article suggests that one of the mechanisms by which this is accomplished is via glut-4 translocation to the cell membrane. Glut-4 acts as the “mitt” that cells put out to catch glucose as it floats by, thereby lowering levels in the bloodstream and allowing for an energy source in the cell.

Nutrition.org — Abstracts: Cefalu et al. 132 (6): 1107

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INSULIN RESISTANCE LEADS TO INFLAMMATION – (11-21-05)

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Plasma IL-6 concentration is inversely related to insulin sensitivity, and acute-phase proteins associate with glucose and lipid metabolism in healthy subjects

What a tangled web we weave…It is known that insulin resistance leads to inflammation (hyperinsulinemia leads to increased TNF-alpha which turns on inflammation), but this study and several others point to the fact that inflammation also increases insulin resistance. So it becomes a feed forward cycle.

This is one of the reasons why I am against drug therapies like metformin because they do not address the overall levels of inflammation present in the body. Only by addressing lifestyle factors that contribute to inflammation (exercise, increased intake of omega 3 fatty acids, decreased intake of omega 6 fatty acids, heavy metal and chemical avoidance, increased fruits and veggies…) will we be able to control both the inflammation and the insulin resistance.

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SOY INTAKE IS PROTECTIVE FOR THE BONE – (05-15-06)

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Cooperative effects of isoflavones and exercise on bone and lipid metabolism in postmenopausal Japanese women

The study strongly illustrates the brilliant orchestra that is our physiology and how, unless researchers understand this dynamic, the wrong message can make it to the public. The isoflavones in soy have been found to be protective for bone, but not in every study. As it turns out, the isoflavones in soy have to been acted on the correct bacteria in the gut to produce equol. Equol is the compound that has consistently been found to protect bone. So, while soy may be protective to bone, this benefit may be reduced in those patients who have ever been on antibiotics or have a disturbed bacterial flora.

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