High Pressure Induces Superoxide Production in Isolated Arteries
Wow! This article suggests that increased blood pressure alone is enough to start a cascade of damage in the cells lining the arteries. Increased super-oxide without ample antioxidants to quench this free radical will result in further damage to the cell. This damage can begin the infiltration of white blood cells that begin plaque formation. This lends more support to the idea of antioxidant supplementation such as Vit C, E and CoQ10 to lower risk of CVD.
Circulation — Abstracts: Ungvari et al. 108 (10): 1253.