’5-a-day’ fruit and veggies or folic acid-fortified foods on plasma folate and homocysteine. This study is an important idea for the clinicians who have said that multivitamins were unnecessary because we get all the vitamins we need from our diets. First of all, these clinicians need to ask their patients if they are getting the […]
L-5-methyltetrahydrofolate vs folic acid on plasma homocysteine. Oral folic acid needs to be converted by the enzyme MHTFR to 5-MTHF before it can be used by the body in the methylation pathways. As has been previously discussed in Updates, the enzyme MHTFR is a common site of genetic differences, with certain genotypes producing a very […]
Folic Acid Improves Endothelial Dysfunction in Patients With CAD The evidence pointing to homocysteine as an independent risk factor for heart disease and stroke, and the evidence suggesting that folic acid, vitamin B12 and B6 can lower levels is now reaching incredible levels. Every person worried about cardiovascular disease needs to have homocysteine levels checked. […]
Randomized Trial of Folic Acid and Serum Homocysteine Levels The results of this article are not surprising. What is surprising is the levels of folic acid needed to maximize homocysteine reduction. 800 mg. This is a relatively high dose and one that you will almost never find in most multivitamins. The best of the multis […]
Empiric Folate Therapy Over Testing for Folate Levels in Macrocytosis This is really a progressive article with a concept that I support wholeheartedly. Many times I can look at a CBC of a patient who has abnormally high or even normal levels at the high end and treat that patient with Vit B12 and folic […]
