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chronic heart failure

Uric Acid and Survival in Chronic Heart Failure – (04-23-03)

December 17, 2013 by James Bogash

Uric Acid and Survival in Chronic Heart Failure

I don’t always include articles about new lab values for prognostication of disease until be know how to modify the risk factor, but here we see that, in patient with chronic heart failure, low uric acid levels had a 100% accuracy in predicting that these patients will NOT need transplantation. Can’t beat 100%!

Circulation — Abstracts: Anker et al. 107 (15): 1991

Click here for more information.

Filed Under: Heart Disease Tagged With: chronic heart failure, uric acid

Role of Coenzyme Q10 in Chronic Heart Failure, Angina, and HTN – (08-13-01)

May 5, 2013 by James Bogash

Role of Coenzyme Q10 in Chronic Heart Failure, Angina, and HTN

It’s nice to see CoQ10 getting some recognition in the pharmacology journals, however, in the conclusion to this article, the author suggests that, while CoQ10 does show some promising results, it is not recommended for use at this time as monotherapy. Huh?? No self respecting physician who understands natural medicine would ever recommend just one thing for cardiovascular disease. It’s a program, not an isolated therapeutic agent. I feel it may be a long while yet before we see natural therapeutics used in trials as they are used in clinical practice.

Pharmacotherapy 21(7):797-806, 2001 Coenzyme Q10 (CoQ10) has a pathophysiologic role in many disease states. The purpose of this review is to provide recommendations regarding the safety, efficacy, and dosing of CoQ10 in the management of chronic heart failure (CHF), angina, and hypertension. Coenzyme Q10 administered orally has favorable actions in the described cardiovascular conditions and appears to be safe and well tolerated in the adult population. Issues concerning optimum target dosages, potential interactions, monitoring parameters, and the role of CoQ10 as a monotherapeutic agent need to be investigated further. Favorable effects of CoQ10 on ejection fraction, exercise tolerance, cardiac output, and stroke volume are demonstrated in the literature; thus, the use of CoQ10 as adjuvant therapy in patients with CHF may be supported. Conclusions: Coenzyme Q10 therapy in angina and hypertension cannot be substantiated until additional clinical trials demonstrate consistent beneficial effects. However, CoQ10 may be recommended as adjuvant therapy in selected patients with CHF. At this time, CoQ10 should not be recommended as monotherapy or first-line therapy in any disease state.

Filed Under: Heart Disease Tagged With: angina, chronic heart failure, coenzyme Q10, HTN, monotherapy

Support the immune system to protect the heart – (01-18-01)

March 17, 2013 by James Bogash

Intravenous Immunoglobulin in Patients With Chronic Heart Failure

The use of therapies to modulate the immune system in chronic heart failure is news to me. But this study shows a benefit in a therapy designed to support the immune system, and shows increased function of the left ventricle with this same therapy. Quite an achievement  Add to this other natural therapies to modulate the immune system, exercise and antioxidants such as CoQ10 and I’m sure the results will improve even further.

Circulation — Abstracts: Gullestad et al. 103 (2): 220

Read entire article here

Filed Under: Strengthen Your Immune System Tagged With: chronic heart failure, CoQ10, Intravenous Immunoglobulin, Strengthen your immune system

CHOLESTEROL AND SURVIVAL RELATED IN CHRONIC HEART FAILURE – (01-05-04)

October 14, 2012 by James Bogash

Relationship between cholesterol and survival in chronic heart failure

Well, now doesn’t this just throw a wrench in the works? Lower cholesterol actually raised mortality rates in patients with chronic heart failure. Research like this really does make us think about our “blinders on” view of medical care today. Especially in light of the recent push to expand the use of statins to include just about everyone with a pulse. Cardiosource –

Read entire article here

Filed Under: Cholesterol Tagged With: cholesterol, chronic heart failure, statins

Fitness Training: 2 Changes to Make in Your Aerobic Training

August 25, 2012 by James Bogash

For decades now, fitness training and aerobic training pushes for hitting your “fat burning” zone and staying there. But what if this has been all wrong?

I believe that the human body was much more attuned for short burst aerobic activity rather than the typical 45+ minutes of continuous exercise. If you think about it– name an animal that we could either chase or would chase us for 40-45-50 minutes and we’d stand a chance of outrunning or catching. You are not going to outrun a saber tooth tiger for 40 minutes, nor are we are going to chase down an antelope for 40 minutes. I just don’t think that, from an evolutionary standpoint, our bodies were designed for long term aerobic activity.

The medical research increasingly favors and supports short-burst aerobic type activities. I can envision us in a hunter-gatherer society, hiding out in a bush. All of a sudden having to jump out and attack an animal, or throw our spear or a rock at whatever we happen to be trying to hunt at that time. I think that our bodies are well attuned to these types of actions.

We also know from a cardiovascular standpoint that, the faster our heart rate comes back down to normal after exertion, the better our cardiovascular health. Thus, the idea of short-burst aerobic type activity really strengthens this association. 

Several recent studies have confirmed the benefits of short burst aerobic activity on aspects of our health:

  1. A single session of short burst aerobic exercise improved diabetics’ blood sugar.
  2. 15 minutes of burst exercise in 2 weeks improved insulin levels by 23%.
  3. A single bout of short burst aerobic exercise lowered blood sugar by 36%.

Ok.  But the devil’s advocates out there would point out that maybe this is good for someone who is otherwise healthy, but what about….say…someone with chronic heart failure?

Surely short burst aerobic exercise will finish off these patients, right?

Dead wrong.  Or rather, anti-dead wrong.

In this particular study, researchers compared two groups of patients who had chronic heart failure:

  • The interval exercise group 3 sessions of 12 repetitions of 30 seconds of exercise at very high intensity, followed by 60 seconds of complete rest
  •  The continual exercise group performed 45 minutes of aerobic exercise

I think in our minds we would be concerned that anyone with chronic cardiac problems should NEVER do high intensity aerobic workouts, and certainly this can’t be better for them than the standard 45 minutes on the treadmill.  Unless, of course, they drop to death from boredom before the 45 minutes are over…

 What did they find?  The burst interval group improved more in every parameter, including:

  • Peak oxygen consumption (Vo2peak)
  • The duration of the exercise test
  • The oxygen pulse
  • Oxygen consumption at the first ventilator threshold (VT1)
  • The distance walked during the 6 minute walk test

In contrast, the constant aerobic exercise group only increased the time at the VT1 and the distance performed at the 6 minute walk test.

Pretty clear difference.

So maybe it’s time to evaluate your aerobic exercise routine and make these two changes:

  1. Make sure you HAVE an aerobic program.  This can be ANYTHING from walking to swimming to jump roping to biking.
  2. Switch to a short burst type rhythm.  30 seconds as fast as you can go with a minute break.  Rinse and repeat 6-10 times.

So what is YOUR favorite type of aerobic fitness activity?

Filed Under: Heart Disease Tagged With: aerobic training, chronic heart failure, fitness training

AM I TAKING ENOUGH FISH OILS?

May 23, 2011 by James Bogash

Typically, the answer is a pretty strong no.  The research on the benefits of healthy fats are all over the board, and this particular study is no exception.  Ever since fats were demonized in the early 90s as a result of the USDA’s food guide pyramid (remember–the one with “fats and oils-use sparingly” at the top while refined carbs were proudly displayed across the bottom?) nutritional experts were warning about the detrimental effects from the lowered intake of omega 3 fatty acids.  They predicted increased rates of cancer, diabetes, heart disease and obesity.  And sure enough, we have seen increased risks of cancer, diabetes, heart disease and obesity (among other chronic diseases).

The most common of the omega 3s are ALA, DHA and EPA.  Each have health benefits of their own.  ALA is principally derived from plant sources such as flax seed, nuts and seeds (pumpkin is high in ALA).  The “fish oils” are DHA and EPA.  Their ultimate source is DHA in algae.  The vegetarian fish eat the algae, leading to higher levels of DHA in the fish.  Salmon is a great example.  These fish are then in turn eaten by large fish like halibut.  The vegetarian fish like salmon, tilapia and trout are the better sources for the omega 3 fatty acids because the mercury content is lower.  But NEVER eat farm raised–farm raised are fed corn (an omega 6 fatty acid), are high in pesticides and are dyed with a dye to give the “natural” color (wild caught salmon’s pink color is from the carotenoids in their diet).

From a supplement standpoint, it is rare that patients taking fish oils are taking decent dosages.  This particular study, which shows strong benefit in those with chronic heart failure, found most benefit from 4 GRAMS per day.  Not four capsules, but 4 grams.  In many cases, the capsules will contain anywhere from 300 mg to 740 mg, depending on strength.  Do the math–this could mean up to 13 capsules per day if it is the cheaper, less strength, supplements.

http://www.sciencedirect.com/science/article/pii/S0002870311001645

Filed Under: Fish Oils, Heart Disease Tagged With: ALA, chronic heart failure, DHA, EPA, fish oils, omega 3 fatty acids

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