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atopy

Urban living environments in atopy and enhanced eosinophil activity – (03-22-01)

September 15, 2013 by James Bogash

Urban living environments in atopy and enhanced eosinophil activity

An interesting point brought up in this article is that the use of electric air conditioners increased risk of atopy (allergic symptoms). The bottom line here is that our kids are no longer getting the fresh air they used to. We’re so stuck on computers and TV that we forget to go out and enjoy the sunshine; and it’s having a negative impact on our health.

Synergy : Allergy 56 (3), 224-230

Read entire article here

Filed Under: Allergies Tagged With: atopy, eosinophil

Food allergy/intolerance: associations with other manifestations of atopy – (11-29-01)

August 11, 2013 by James Bogash

Food allergy/intolerance: associations with other manifestations of atopy

This is another wonderful article packed full of interesting concepts. First is finding out just how common food allergy is in the general population. This article also gives some common food allergens found which includes certain nuts, milk and fruits. Another common theme arises here as well–systemic manifestation of food allergy resulting in reactions in the GI tract, skin and oral cavity. Skin reactions were found in 28.7% of the allergic patients. This brings to mind one of my patients with eczema whose PCP told her that food does not have any relation to her symptoms. According to this study that’s just plain not true. Any patient with dermatological problems should be put on an elimination diet to see if food allergies has any contribution to symptoms. What does the patient have to lose?? Maybe the skin lesions…. Synergy : Allergy 56 (12), 1172-1179

Read entire article here

Filed Under: Food Allergy Tagged With: allergic patients, atopy, Eczema, food allergy, PCP

Development of a strong Th2 profile in high-risk children w/ atopy – (07-12-01)

July 21, 2013 by James Bogash

Development of a strong Th2 profile in high-risk children w/ atopy

Looking at another aspect of healthy Th1/2 balance, this article suggests that the first 6 months of an infants’ development is essential to creating a healthy balance. Maybe the studies that looked at antibiotic use connected to asthma should only look at it’s use in the first six months. It would be surprising if the data shifted even more convincingly towards being causative. Also, in the first six months of life, just how many vaccines do you think a newborn is exposed to? How about hep B? Hep B is mainly transferred through blood-blood contact in IV drug users and unprotected sex, and also in health care workers exposed to blood. Know many 3 month olds that partake in this behavior? No…? So why do we need a sweeping mandate to vaccinate them all?

Synergy : Clinical & Experimental Allergy 31 (7), 997-1006

Read entire article here

Filed Under: Vaccination Tagged With: atopy, Th2 profile, vaccinate

Breastfeeding Linked to Increased Risk of Atopy and Asthma – (04-23-01)

June 27, 2013 by James Bogash

Breastfeeding Linked to Increased Risk of Atopy and Asthma

This is one of those articles that the media will love to use to try to scare the heck out of mothers. However, much like the vitamin C research that shows an increase in DNA damage (further delving revealed that vitamin C also protects against more severe and damaging types of DNA damage…) one study does not set the standard in stone. While I can’t think of a rationale as to why the use of a therapy deemed highly beneficial would show a negative relationship. It would be interesting to evaluate the diets of the mothers for potential allergens that the infant would be exposed to…

57th Annual Meeting of the American Academy of Allergy, Asthma and Immunology Dr. Malcolm R. Sears from McMaster University in Hamilton, Canada and colleagues assessed the impact of breastfeeding on the development of atopy and asthma by comparing data on 504 subjects who were breastfed for at least 4 weeks with data on 533 subjects who were not. Skin testing at age 13 revealed that breastfed subjects were significantly more likely than their counterparts to have a positive reaction to cat, dust mite, or any tested allergen. In fact, this effect was evident on repeat testing at age 21 years. In addition, breastfed subjects were more than twice as likely as their cohorts to have been diagnosed with asthma by 9 years of age. The effects of breastfeeding seen at 13 years of age were independent of maternal or paternal history of atopic disease, first born or non-first born status, and gender, the researchers note. However, at age 21 years the effects were most evident and significant in male subjects. “The majority of review papers and advice given says breastfeeding is good because it reduces your risk of developing allergy and asthma,” Dr. Sears told Reuters Health. “However, the evidence is mixed and our study, which analyzes a New Zealand cohort, found just the opposite effect,” he said. “Our study differs from previous studies in that the prior studies were short term and often looked at early childhood wheezing which often is not allergic-based,” Dr. Sears pointed out. “We know that breastfeeding reduces the likelihood of infection; therefore it may have improved the outcome for infection-based wheezing,” he explained.

Filed Under: Asthma, Vitamin C Tagged With: asthma, atopy, vitamin C

Cytokines in peripheral whole blood in atopic, nonatopic asthmatics – (12-07-00)

June 17, 2013 by James Bogash

Cytokines in peripheral whole blood in atopic, nonatopic asthmatics

This article touches on the importance of Th1/Th2 cytokine balance. I’ve actually come up with a good description of these two balances. Th1 is the body’s attack system, attacking invaders that make it into the body. Th2 is the defense system, trying to keep things from getting in. A Th2 dominant state will overreact to invaders, thus leading to atopy and asthma. There are natural ways to help balance the Th1/Th2 ratio.

Synergy Abstract

Read entire article here

Filed Under: Asthma Tagged With: asthma, atopy, Cytokines, nonatopic asthmatics, TH1, Th2

Clostridium difficile, atopy and wheeze during the first year of life – (11-21-02)

March 22, 2013 by James Bogash

Clostridium difficile, atopy and wheeze during the first year of life

More and more evidence is supporting the idea that a healthy bacterial population is essential for normal development of an infant’s immune system. Here we see that C. difficile may increase risk of allergies. Well, it is well known that C. difficile can be a result of antibiotic use. Not only this, but antibiotics will kill off the bacteria that is supposed to be there in the first place. When it comes to antibiotic use, physicians need to view each case with the potential long term consequences. I think the idea that antibiotics are benign is still highly prevalent, and a change in the current thinking is needed.

Synergy Abstract

Read entire article here

Filed Under: Allergies, Strengthen Your Immune System Tagged With: allergies, atopy, Clostridium difficile, Strengthen your immune system

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