LifeCare Chiropractic

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TH1

Role of INF-gamma in promoting Th 1 responses in coeliac disease – (02-26-01)

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Role of INF-gamma in promoting Th 1 responses in coeliac disease

Coeliac disease is an allergy to gluten, primarily found in wheat. Coeliac disease is the result of a Th1 cytokine response–the branch of the immune system that is responsible for the “attack” mode towards invaders. By continuing to eat wheat that the body is allergic to, a patient with coeliac disease will perputuate this unbalanced reaction of the immune system; potentially effecting other systems in the body. Coeliac disease has been linked to Alzheimers, diminished bone mass and neurological problems (ataxia) among others. Avoiding gluten is a foundation in any functional medicine approach to health.

Gut — Abstracts: Monteleone et al. 48 (3): 425

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The protective effect of childhood infections – (03-01-01)

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The protective effect of childhood infections

This is a nice editorial reviewing the importance of childhood infections in developing a healthy and balanced immune response in children. Remember that, on top of antibiotics and a more sterile environment not giving an infant’s Th1 response a chance to develop and mature, vaccinations are leading to a unbalanced, overdeveloped Th2 response. This has the potential to lead to such problems and allergy and asthma. The authors in this article do make a serious mistake, however. They suggest that science come up with some way to mimic the body’s response to infections through vaccination or passive immunotherapy. I just have to shake my head at the arrogance of science and medicine when it comes to trying to improve on nature.

bmj.com Johnston and Openshaw 322 (7283): 376

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original article that editorial was based upon: bmj.com Abstracts: Illi et al. 322 (7283): 390

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Cytokines in peripheral whole blood in atopic, nonatopic asthmatics – (12-07-00)

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Cytokines in peripheral whole blood in atopic, nonatopic asthmatics

This article touches on the importance of Th1/Th2 cytokine balance. I’ve actually come up with a good description of these two balances. Th1 is the body’s attack system, attacking invaders that make it into the body. Th2 is the defense system, trying to keep things from getting in. A Th2 dominant state will overreact to invaders, thus leading to atopy and asthma. There are natural ways to help balance the Th1/Th2 ratio.

Synergy Abstract

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Prenatal exposure to bisphenol A up-regulates immune responses – (07-16-04)

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Prenatal exposure to bisphenol A up-regulates immune responses, including T helper 1 and T helper 2 responses, in mice

In English, this article basically re-affirms how important the prenatal and natal periods are in determining the long term health of the child. Sources of BPA are all around us (see http://www.ourstolenfuture.org/NewScience/oncompounds/bisphenola/bpauses.htm) and our risk of exposure are high.

According to this study (which was done on mice), BPA really messes with the immune system–up – regulating BOTH TH1 and TH2 immune response (TH1 upregulation = autoimmune diseases, TH2 = allergies/asthma) although the TH1 response was greater. With chronic diseases (like asthma, allergies, rheumatoid arthritis, lupus, MS, etc…) being such as issue in the health of our nation today, anything we can do to lower the risk is important, and it needs to start in pregnancy.

Prenatal exposure to bisphenol A up-regulates immune responses, including T helper 1 and T helper 2 responses, in mice – Immunology –

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