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Celiac Disease

Risk of Non-Hodgkin Lymphoma in Celiac Disease – (04-08-02)

June 14, 2013 by James Bogash

Risk of Non-Hodgkin Lymphoma in Celiac Disease

Allergy to gluten, a storage protein found in several grains (most notably wheat), has been all over the medical literature lately. Here we see a 3x increased risk for NHL. We need to start evaluating more regularly for celiac disease. Currently, a blood test called transglutaminase is one of the best ways to evaluate for this condition.

Read entire article here

Filed Under: Allergies, Celiac Disease Tagged With: Allergy, Celiac Disease, Gluten, Non-Hodgkin Lymphoma, transglutaminase

Neurological complications of coeliac disease – (08-05-02)

May 18, 2013 by James Bogash

Neurological complications of coeliac disease

While this is only a short abstract of a larger review article, it cements the fact that allergy to gluten containing grains (mainly wheat) can have a major impact on the rest of the body; in this case the neurological system. Chalk up effects on the GI system, skin and increased auto-antibodies to thyroid. If patients are unsure, an elimination diet avoiding wheat for at least 2 wks can be used. The beauty of an approach like this is that no one I’ve ever recommended an elimination diet for has ever died… If you don’t like this approach, serum transglutaminase levels can be used as a marker for coeliac disease.

Postgrad Med J — Summaries: Pengiran Tengah et al. 78 (921): 393

Read entire article here

Filed Under: Celiac Disease Tagged With: Coeliac disease, Gluten, neurological system, serum transglutaminase levels

Brain White-Matter Lesions in Celiac Disease – (08-13-01)

May 5, 2013 by James Bogash

Brain White-Matter Lesions in Celiac Disease

If this article does not give you an idea of how important it is to recognize the impact of food allergies on our overall health, I’m not sure what will. Reactions to food allergies can range from minor GI irritation to irreversible brain damage. Physicians need to begin to recognize the impact that the GI tract has on our overall health. The author suggests that this response is mediated through an upregulation of the immune system leading to focal damage in the brain. Consider this…many people crave the foods they’re allergic to and so eat them very often. That leaves opportunities on almost a daily basis to wreak havoc on our immune systems…

Pediatrics — Abstracts: Kieslich et al. 108 (2): e21

Read entire article here

Filed Under: Celiac Disease, Food Allergy Tagged With: Celiac Disease, food allergies, immune systems

Coeliac disease in the father affects the newborn – (08-13-01)

May 5, 2013 by James Bogash

Coeliac disease in the father affects the newborn

Wow!! Forever the male has been viewed as rather unimportant in the health of the fetus, and yet several studies are starting to show that this is far from true. In this case, coeliac disease (allergy to gluten proteins most commonly found in wheat), whether treated or untreated has an effect on the birthweight. While I would find it hard to follow a pathway that would lead to a defect in the sperm resulting in this outcome, coeliac disease may be a factor that is transferred to the fetus and has a rapid phenotypic expression in the developing fetus.

Gut — Abstracts: Ludvigsson and Ludvigsson 49 (2): 169

Read entire article here

Filed Under: Celiac Disease Tagged With: Coeliac disease, phenotypic expression

Avenin fails to induce Th1 response in coeliac tissue – (12-12-02)

March 26, 2013 by James Bogash

Avenin fails to induce Th1 response in coeliac tissue

The debate has been extensive as to whether oats are safe for patients with coeliac disease (a condition in which the body reacts to the protein gliaden, which is most abundant in wheat). Most articles seem to support the idea that oats are safe for patients with coeliac disease.

Gut — Abstracts: Kilmartin et al. 52 (1): 47

Read entire article here

Filed Under: Celiac Disease Tagged With: Avenin, Coeliac disease, gliaden

Food allergies exist and are major contributors to chronic disease – (06-09-03)

March 17, 2013 by James Bogash

Celiac neuropathy

With the virtual avoidance of the fact that food allergies exist and are major contributors to chronic disease, this study has the potential to change the way many doctors view allergies. Unfortunately, they would have to read the article first….

This article reminds me of a patient I had awhile back that had been diagnosed with dermatitis herpatiforms–a skin condition closely linked to celiac disease–10 yrs prior. When he asked his doctor if he should avoid wheat, the doctor said that would be too hard and put him on a drug used for leprosy. Forget the long term damage that a food allergy like this could cause on other organ systems.

Neurology — Abstracts: Chin et al. 60 (10): 1581

Read entire article here

Filed Under: Celiac Disease Tagged With: Celiac Disease, Celiac neuropathy, food allergies, herpatiforms

Changing face of adult coeliac disease – (01-24-02)

March 10, 2013 by James Bogash

Changing face of adult coeliac disease

The concept of coeliac disease having a major impact on overall health is just beginning to gain speed. Many neurological conditions can be related to something as simple as wheat allergy. Remember that coeliac disease is an allergy to gluten, a protein found in certain grains, most notably wheat. Interestingly, when wheat is grown in a high nitrogen content source (i.e. non-organic, highly fertilized soil) that plant takes up the extra nitrogen and uses production of proteins as a storage route–in this case leading to excess gluten. An elimination diet is such an incredible and safe tool to be used for a wide variety of conditions…

Postgrad Med J — Summaries: Sanders et al. 78 (915): 31

Read entire article here

Filed Under: Celiac Disease, Food Allergy Tagged With: Coeliac disease, wheat allergy

No harm from five year ingestion of oats in celiac disease – (02-11-02)

March 3, 2013 by James Bogash

No harm from five year ingestion of oats in celiac disease

Oats do contain some gluten which has always prompted the recommendation to stay away from oats in patients with celiac disease. I have always found these tough recommendations and have allowed patients to eat oat on an elimination diet. I am glad that current research seems to support this concept. Given how prevalent gluten insensivity is and how hard it is to eliminate just wheat without any thought to also eliminating oats, this finding will make life a little easier on some patients.

Gut — Abstracts: Janatuinen et al. 50 (3): 332

Read entire article here

Filed Under: Celiac Disease Tagged With: Celiac Disease, gluten insensivity

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