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Sulforaphane

Autism Spectrum Disorder: Help from an Unexpected Source

November 12, 2014 by James Bogash

natural cures for autism
Photo courtesy of https://www.flickr.com/photos/mindwhisperings/

There was a recent news story of a mother who threw her 6 year-old autistic son to his death off of a bridge.

While this heinous act was performed by a mentally disturbed woman, her reasoning was heartbreaking.  She couldn’t bear the idea of her child regressing back into himself as he had done so many times in the past.

As a father, even the thought of losing a child’s outward reaction to his or her environment and experiencing the joys and pains as they grow is hard to imagine.

For the parents who do have children that fall under the autistic spectrum disorders category, there are things that can be done.  There are many amazing behavioral programs that, if instituted early, can increase the likelihood of your child fully integrated into higher grade levels.

There are also a large number of approaches designed to improve the health of the brain, irregardless of any labels that may be attached to that brain.  Nutrition and supplementation plays a huge role here, as you can see from this particular study.

In it, researchers looked at the use of sulforaphane in autistic spectrum disorders.  Sulforaphane is one of the principal components found in broccoli.  And, as you know, broccoli is an interdimensional warp, containing several pounds of incredibly good-for-you natural chemicals in every tree-resembling ounce.

They took 44 young men (aged 13–27) with moderate to severe ASD and gave them either sulforaphane derived from broccoli sprout extracts or a placebo for 18 weeks.  Behavior was evaluated three behavioral measures completed by parents/caregivers and physicians: the Aberrant Behavior Checklist (ABC), Social Responsiveness Scale (SRS), and Clinical Global Impression Improvement Scale (CGI-I).

Here’s what they found:

  • After 18 weeks, the placebo group had minimal change (<3.3%).
  • The sulforaphane group had substantial improvement of behavior: 34% for ABC and 17% for SRS scores.
  • On CGI-I, a greater number of the sulforaphane group had improvement in social interaction, abnormal behavior, and verbal communication.
  • Four weeks after discontinuation of sulforaphane, the scores slid back toward pretreatment levels.

Researchers noted that they picked sulforaphane “because of its well-known ability to reverse abnormalities that have been associated with ASD, including oxidative stress and lower antioxidant capacity, depressed glutathione synthesis, reduced mitochondrial function and oxidative phosphorylation, increased lipid peroxidation, and neuroinflammmation.”

That’s a pretty tall order for a natural compound that had no side effects.  We are talking about improving the health of the brains of our children and protecting them against further damage.

Being a “lifestyle” person, I would prefer to load our kids up with broccoli and cauliflower, but the amount of sulforaphane given in this study would equate to a relatively large dose of broccoli sprouts (which have a higher content of sulforaphane) and even this would depend largely on storage and cooking method.  Sometimes, we just have to accept that the pharmaceutical model of taking a bioactive compound, concentrating it and using it to treat something may be the best bet.

The big difference is that the drug companies take that natural compound and try to figure out some way to change it slightly so it can be patented.  This opens up the door to side effects that just aren’t seen in the original natural compound.

 

Filed Under: Autism Tagged With: autism, autistic spectrum disorder, broccoli, Sulforaphane

Sulforaphane, H pylori and stomach tumors – (06-10-02)

June 14, 2013 by James Bogash

Sulforaphane, H pylori and stomach tumors

This study finds that a substance found in broccoli has the ability to inhibit H pylori infection as well as blocking stomach tumor formation from the H. pylori. We spend so much time in research looking for ways to kill off this bug and whether this triple-therapy regimine is better than that one and so on. I’ve said it before and I’ll say it again here–it is slowly appearing that H pylori is just a manifestation of poor lifestyle choices. We already know that low vitamin C in gastric juice is found in patients with H pylori. Now we see that compounds in broccoli are inhibitory for the growth of this bug. Give my theory a few years for the research to catch up and you can say casually that you knew about that years ago to all your friends…

PNAS — Abstracts: Fahey et al. 99 (11): 7610

Read entire article here

Filed Under: Tumors and General Cancer Tips, Vitamin C Tagged With: h. pylori, stomach tumors, Sulforaphane, vitamin C

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