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licorice

CONJUGATED LINOLEIC ACID LOWERS CANCER RATES – (11-30-03)

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Conjugated Linoleic Acid Inhibits Cell Proliferation through a p53-Dependent Mechanism

Remember that CLA is formed in ruminent animals by the action of gut bacteria on certain fatty acids (NOT from the typical “corn-fed” diet of todays’ livestock). This would mean that, in the past, CLA levels were high in the milk and meat of livestock. However, with todays’ poor farming habits, CLA levels are virtually gone. CLA has an action similiar to the licorice noted above–affects PPAR-gamma receptor sites, and as such has a broad spectrum beneficial effect on health. We already know CLA lowers certain cancer rates–now researchers are starting to work towards the “how” portion of the puzzle.

nutrition.org — Abstracts: Kemp et al. 133 (11): 3670.

Read entire article here

EFFECTS OF LICORICE ON THE ORPHAN NUCLEAR RECEPTOR PPAR GAMMA – (11-30-03)

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Licorice Ethanolic Extract with PPAR-gamma Ligand-Binding Activity Affects Diabetes, Abdominal Obesity and Hypertension

This animal study gives results of the effects of licorice on the orphan nuclear receptor (so named because we previously were not sure what these genes did when they were turned on) PPAR-gamma. Keep in mind that we are only beginning to understand what these genetic receptors due, but we do know that they are a foundation upon which many aspects of our health (and disease) are built, so any compound affecting these receptors has the ability to impact several disease states. Conjugated linoleic acid and omega-3 fatty acids also affect these receptors. As a side note, this is not the sugar-laden licorice we find in today’s licorice ropes–this is the real stuff.

nutrition.org — Abstracts: Mae et al. 133 (11): 3369.

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WHAT ARE THE PROBLEMS OF VIRAL INFECTIONS? – (05-01-05)

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Glycyrrhizic acid alters Kaposi sarcoma–associated herpesvirus latency, triggering p53-mediated apoptosis in transformed B lymphocytes.

Wow.  One of the problems with many viral infections is that they incorporate themselves into our own DNA so we can’t find them.  This makes it difficult to find these contaminated cells and eradicate them.

This study suggests that glycyrrhizic acid (from licorice) may be able to help the body recognize these contaminated cells.

Read entire article here