Higher Estrogen Linked to Decreased Homocysteine
This may be one of the routes by which estrogen is known to lower risk of heart disease. Of course, supplementing with folic acid, Vit B12 and B6 will also lower levels of homocysteine WITHOUT increasing your risk of breast and endometrial cancer.
Am J Epidemiol 2000;152:140-148 Data from the Third National Health and nutrition Examination Survey (NHANES III) indicate that estrogen status is inversely related to total homocysteine concentration, a risk factor for vascular occlusion. “Perhaps supplementation with estrogen would be beneficial to women by lowering their homocysteine concentration and thereby lowering their risk of heart attack and stroke,” Dr. Morris said. But, she cautioned, “this was a descriptive study, so one cannot draw clinical conclusions about the benefits of estrogen supplementation.”