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reflux disease

Baclofen on 24 hour pH metry and symptoms in GERD – (05-05-03)

December 2, 2013 by James Bogash

Baclofen on 24 hour pH metry and symptoms in GERD.

Okay, so it is interesting that a muscle relaxer such as baclofen has a beneficial effect on reflux disease. However, what I find particularly disconcerting is that this class of drugs raised the pH of the stomach (essentially lowered acid production). Given that many patients (with and many without GI complaints) do not make enough stomach acid, the fact that a drug unrelated (at least until this study..) to acid production would interfere with this essential physiologic action opens up a wide Pandora’s box of downstream mayhem.

Gut — Abstracts: Ciccaglione and Marzio 52 (4): 464

Filed Under: Uncategorized Tagged With: baclofen, GERD, muscle relaxer, reflux disease

H. pylori eradication and NSAIDs: effects on ulcers – (08-10-00)

November 12, 2013 by James Bogash

H. pylori eradication and NSAIDs: effects on ulcers

First, I think that there are too many questions about H. pylori’s effect on ulcers. Some researchers say it is supposed to be there, some say H. pylori is an infection and needs to be medicated, yet others suggests that H. pylori protects against reflux disease. Next, (and here comes my chiropractic viewpoint) what is the reason the patient is taking the NSAIDs and can the problem be fixed so the drug is not needed??

Alimentary Pharmacology & Therapeutics 14 (7), 879-885 Eradication of H. pylori prior to NSAID therapy significantly reduces the level of apoptosis in the gastric mucosa, which may contribute to maintaining mucosa integrity and preventing ulcer development.

Filed Under: NSAIDs Dangerous Tagged With: h. pylori, NSAIDs dangerous, reflux disease

Lymphoma and H. pylori – (08-28-00)

June 20, 2013 by James Bogash

Lymphoma and H. pylori

Eradicating H. pylori may help send certain lymphomas into remission. We need to be careful with all this info on H. pylori. Some studies show benefits with eradication and yet others show increase risk of other diseases such as reflux disease. Some consider H. pylori a pathogen, and yet others consider it normal flora that is supposed to be there. I think this issue needs to be very, very carefully researched before we make any final judgement on this bacteria.

Read entire article here

Filed Under: Miscellaneous Tagged With: h. pylori, Lymphoma, reflux disease

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