LifeCare Chiropractic

The Best Chiropractic Care in Mesa, Arizona

Celebrex

ANTI INFLAMMATORY DRUGS INCREASE HEART ATTACK RISKS – (06-27-05)

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Myocardial infarction in patients taking COX-2 inhibitors or conventional NSAIDs

Well, one thing we can say about the debacle of the selective COX-2 inhibitors like Vioxx and Celebrex is that they have brought to light a rather startling discovery.  ALL these anti-inflammatory drugs increase risk of heart attacks.

So, with the extremely high use of this class of drugs, just how many heart attacks out there have been a direct result of taking typical NSAIDs like ibuprofen?  The number is probably incredibly high.

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DANGERS OF NSAIDs ON THE STOMACH – (08-28-06)

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Comparing Rates of Dyspepsia with Coxibs vs NSAID+PPI: A Meta-Analysis

Man, this gets confusing. Several years back, we saw the appearance of “public service” ads talking about the dangers of NSAIDs on bleeding ulcer risk and death. Noting that some 22,000 people a year die from this complication, the “public service” ad was directing the general public, who had no idea their ibuprofen could kill them, the find more information.

Little did the general public know that this “educational process” was designed to introduce callers to a new class of drugs called the COX-2 inhibitors like Vioxx, Celebrex and Bextra, that were safer on the stomach. The cost of these drugs was exceedingly expensive, and nearly bankrupted the healthcare system in Australia and led to phenomenal profits for the drug companies. The rest of the story most are familiar with–Merck is fighting off lawsuits because Vioxx had the unintended consequence of increasing risk of heart attacks.

So now, come full circle, we have this study that finds that, giving standard NSAIDs along with another drug to protect the stomach is actually much better on the stomach than the COX-2 inhibitors. Geezz!! How ’bout finding a good chiropractor to reduced the arthritis pain instead???

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BENEFICIAL EFFECTS ON CHOLESTEROL CONCENTRATIONS – (11-05-07)

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Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations

A major paradigm shift has occurred w/in the pharmaceutical company lately. For the past however many years, pharma companies have put out “blockbuster” drugs–high dollar drugs like Celebrex and Neurontin that, in reality, don’t add much new to the treatment possibilities. The development of these drugs is very expensive, but the payoff is vast. But a funny thing happened on the way to the bank.

The most recent of these drugs that was believed to be a blockbuster in CVD treatment was to raise HDL levels. The human trials were a dismal failure, leading some to speculate that the end of the blockbuster days were over. Can’t say I’d lose any sleep. One the far end of the scale from the blockbuster, high cost drug, in this study we find that good ‘ole fashioned cocoa powered raised HDL levels by 24%, all without killing a single study participant.

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