High-Dose Vit E Reduces Serum Levels of CRP in Diabetes
It is not surprising that Vit E may have the potential to lower the risk of heart disease in diabetics. What is surprising is that this study actually used levels considered therapeutic by researchers…1200 IU/day.
Free Radic Biol Med 2000;8:790-792 Results of a new study of type-2 diabetics indicate that high-dose vitamin E reduces levels of C-reactive protein (CRP), a marker of inflammation and a predictor of cardiovascular disease. “High dose vitamin E in all three groups reduced inflammation as seen by low levels of C-reactive protein, which we measured by a new highly sensitive assay,” Dr. Jialal told Reuters Health. The researchers also saw lower levels of the pro-inflammatory cytokine, interleuken-6, which drives CRP. Both markers, Dr. Jialal explained, have previously been shown to be predictors of heart disease and stroke. “We have shown that you can modulate these markers in diabetics, which has great implications, given that in diabetes you have at least a 2-fold increased prevalence of stroke and heart attacks,” he added.