Does oxidative damage to DNA increase with age? – (09-02-01)



Does oxidative damage to DNA increase with age?

This is such an insightful article that opens up both questions and answers. Although this is also a rodent study, once again evidence is strong in support of similar effect in humans. First, do we have increased DNA damage with aging, or does the DNA damage lead to aging? Probably a mixture of both. Current theories of aging include oxidative damage, glycosylation of proteins and shortening of telomeres. Most likely, aging is a combination of all these factors and more. The increased oxidative stress to DNA may be more of a reduction in the protective factors present with younger patients.

PNAS — Abstracts: Hamilton et al. 98 (18): 10469

Read entire article here

James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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Categories: Anti-Aging, Oxidative Stress
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