USE OF COX-2 AGAINST KNOWN DAMAGES OF NSAIDS – (05-29-03)

Adverse renal effects of anti-inflammatory agents: evaluation of selective and nonselective cyclooxygenase inhibitors. With the sharp increase in COX-2 use such as Celebrex and Vioxx (most of this use being inappropriate for its indications), we really need to evaluate the selective COX-2 inhibitors against other known damages from NSAIDs. Here we see that the COX-2 […]

SODIUM SALT INTAKE ADVERSELY EFFECTS KIDNEY’S EXCRETION OF ALBUMIN – (10-04-04)

Sodium intake affects urinary albumin excretion especially in overweight subjects I have to admit, that I have usually told patients that sodium intake is really not as important as most believe it is (with the exception of processed foods–which are generally higher in sodium). There seems to be only a small percentage of the population […]

IS MORTALITY DECREASING FROM ACUTE RENAL FAILURE? – (09-06-05)

Has mortality from acute renal failure decreased? We generally think of medical research as a good thing.  Billions of dollars go into new approaches, new treatment, new methods of detection.  But do they really change things?  In many cases, the answer is no.  How many untold billions have gone into AIDS research without anything even […]

CYANOCOBALAMIN RAISES COBABLAMIN LEVEL IN BLOOD – (10-20-05)

Comparative effects of hydroxocobalamin and cyanocobalamin on plasma homocysteine concentrations in end-stage renal disease This issue of cyanocobalamin has come up once before a few years back, but it was enough to give me cause for concern. The study suggested that cyanocobalamin actually inhibited one of the enzymes it was supposed to be helping. This […]