Comparative effects of hydroxocobalamin and cyanocobalamin on plasma homocysteine concentrations in end-stage renal disease

This issue of cyanocobalamin has come up once before a few years back, but it was enough to give me cause for concern.

The study suggested that cyanocobalamin actually inhibited one of the enzymes it was supposed to be helping.

This study did not look at this enzyme affect, but it did find a much stronger effect of raising cobablamin levels in the bloodstream with hydroxy vs cyano (40 fold increase vs 10 fold increase).

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James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.