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GI cancers

H. Pylori May Protect Against Diarrheal Disease in Children – (12-14-00)

June 27, 2013 by James Bogash

H. Pylori May Protect Against Diarrheal Disease in Children

I still remain on the fence about H. pylori. The is too much evidence both pro and con for the presence of this organism. A few questions need to be answered before we indiscriminantly eradicate H. pylori in every patient. Is H. pylori normal flora? How does transmission/infection take place? What percentage of healthy persons have H. pylori and no conditions associated w/ it? Current standard of care is to eradicate whenever found. It may be that in 20 or 30 years we will find that H. pylori protects against some GI cancers and may even act as a sentry for infection from other organisms. We just don’t have enough data yet.

J Infect Dis 2000;182:1446-1449 An inverse relationship has been observed between Helicobacter pylori colonization and diarrheal disease in children. According to the results of a population-based study published in the November issue of the Journal of Infectious Diseases, these findings suggest that H. pylori may protect against gastrointestinal infection. The results of previous studies have suggested that H. pylori infection protects against colonization by other bacteria by inducing the production of immunoglobulin A and secreting its own antibacterial peptides, Dr. Dietrich Rothenbacher, from the University of Ulm, Germany, and colleagues explain. Dr. Rothenbacher’s group points out that “although certain H. pylori strains are associated with increased risk of illnesses…in adult Western populations, it may well be that the benefits of colonization in most carriers outweigh the costs, since only a small proportion of H. pylori carriers develop clinically related diseases during any time during their life.” The investigators believe the findings, if confirmed, “could substantially change management and prevention strategies, especially for children in the developing world, where both diarrheal illnesses and H. pylori are highly prevalent.”

Filed Under: Diarrhea / Constipation / Irritable Bowel Tagged With: Diarrheal Disease, GI cancers, h. pylori

STEAM COOKING SIGNIFICANTLY IMPROVES IN VITRO BILE ACID (02-23-09)

February 12, 2012 by James Bogash

Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage

This is an interesting study that look at how steam cooking effects the ability of certain foods to bind to bile acids. Remember that bile acids are produced by the liver from cholesterol and stored in the gallbladder until needed. When our body needs to make more bile acids, we use cholesterol from the liver, essentially lowering it’s potential circulation in the serum.

So, not only would the binding to bile acids remove this cholesterol from circulation, but these bile acids, if left alone in the GI tract, are irritating to the lining of the GI tract and can increase the risk of certain GI cancers (that’s one of those little gems they NEVER seem to tell patients who have their gallbladders removed…). So, these vegetables, when steamed, actually had a greater ability to bind the bile acids and have the dual effect on circulating cholesterol as well as protecting the GI tract.

Read entire article here

Filed Under: Cancer, Cholesterol Tagged With: bile acids, cholesterol, GI cancers, GI tract, steam cooking

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