Cyclo-Oxygenase 2

Risk of adverse gastrointestinal outcomes in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs

Isn’t this just the biggest kick in the gluts? A new class of drugs, the selective COX-2 inhibitors like Vioxx and Celebrex are born and a market created by clever marketing campaigns to let people know that the “other” anti inflammatories can damage the GI tract. These drugs get handed out like candy, nearly bankrupting healthcare in some countries due to their high cost. Soon the evil side is seen in an increased tendency to clot the blood, leaving tens of thousands dead. Here’s the kicker—it may turn out that this class of drugs is not so good at doing what it was supposed to do better!! Run that by the widows and orphans whose loved ones suffered untimely deaths.

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