This is one of the best ways to combine the best of nutrition w/ the best of Western medicine. But don’t hold your breath waiting for it to become standard prescription practice. Investigational studies of a formulation of extended release niacin and lovastatin show that the combination is safe and well-tolerated and that it improves […]
NSAIDs, First Occurrence of Heart Failure and Relapsing Heart Failure I was not aware that NSAIDs will increase risk of recurrent attacks of heart failure, but it appears that this risk is quite substantial. This definitely fits the mold of the new selective COX-2 inhibitors increase risk of heart failure. Remember that we do not […]
Metaanalysis of Severe Upper GI Complications of NSAIDs This huge review of available literature identifies a 3x greater risk of severe GI bleed with NSAID use. This included as little as four days of use. We need to stop thinking of NSAIDs as benign drugs used to treat everything from minor headache to severe pain. […]
Adverse renal effects of anti-inflammatory agents: evaluation of selective and nonselective cyclooxygenase inhibitors. With the sharp increase in COX-2 use such as Celebrex and Vioxx (most of this use being inappropriate for its indications), we really need to evaluate the selective COX-2 inhibitors against other known damages from NSAIDs. Here we see that the COX-2 […]
Prescriptions for Chronic High-Dose Cyclooxygenase-2 Inhibitors are Often Inappropriate and Potentially Dangerous How much MORE apparent does it have to be that physicians are not reading their own literature? We’ve learned that the COX-2 class of drugs is very expensive, has minimal benefit over other NSAIDs and has significant cardiovascular risk, and yet there’re STILL […]
