Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances

I know that when I hear melatonin, I used to only think of a natural hormone that can help with sleep. Now, years later, we’ve found so many other physiologic roles for melatonin. It’s a very strong antioxidant in the brain; it’s found in certain vegetables; and now, helps to regulate GI motility.

As such, in this study, 3 mg at bedtime lowered abdominal pain in patients with IBS. Interestingly, there were no beneficial effects on sleep quality. While this may not have had a bearing, I have recently moved to starting patients on a lower (.5 mg) dose to start with and this seems to result in less side effects.

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James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.