Homocysteine, cystathionine, MMA for diagnosis of vitamin deficiency
I have come across many patients who had “normal” blood levels of Vit B12 and yet responded positively to high dose B12 and folic acid. Our current laboratory values for B12 are set much too low and clinicians are not recognizing this. This study suggests that other markers are much better at diagnosing vitamin deficiency than serum levels. My recommendation….some companies make excellent and inexpensive 2000mcg B12/folate supplements; some of these labs tests are very expensive. If you consider a B12 or folate deficiency, supplement it.
Synergy Abstract