COX-2 inhibitors delay gastric wound healing in rats – (09-07-00)



COX-2 inhibitors delay gastric wound healing in rats

Evidence is starting to accumulate on the potential adverse effects of these new anti-inflammatories. This article suggests that, even though they lower your chances of getting an ulcer, COX-2 may hinder any ulcer that were already present from healing.

Journal of Gastroenterology and Hepatology 15 (7), 752-761 The present study demonstrated that cyclo-oxygenase-2 inhibitors delay gastric wound healing by suppressing expansion of the mucosal proliferative zone. These results provide evidence that cyclo-oxygenase-2 has an important role in gastric mucosal regeneration.

James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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Category: Gastroenterology
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