Semiquinone radical intermediate in catecholic estrogen-mediated cytotoxicity and mutagenesis: Chemoprevention strategies with antioxidants
Had to leave the long title for effect… I know this goes into some heavy biochemistry, but the take home message is this… A woman (and a man to a lessor degree) are at risk from the breakdown of her of estrogens. These are not benign compounds that do only good things. Their breakdown, if unfavorable, can strongly increase risk of DNA damage and several types of cancer. This article shows that this risk can be lowered with antioxidants and diets high in fruits and veggies. Cruciferous veggies, additionally, will favorably effect the breakdown of estrogens so that protecting against DNA damage is not even an issue.
PNAS — Abstracts: Samuni et al. 100 (9): 5390