Calorie Restriction Promotes Mitochondrial Biogenesis by Inducing the Expression of eNOS
Despite reading the ads and articles you see everywhere, the ONLY approach that has been shown to improve lifespan in mammals is calorie restriction without nutrient restriction. Period. However, the pharmaceutical companies are looking for what physiological pathways are triggered with caloric restriction so they can make a drug that does the same thing. We want to have our cake and eat it too (all chocked full of refined carbs and saturated fat…), but we definitely, as a society, do not want to do what’s right. Heck, we can’t even do the high protein diets right; we have to load up our favorite foods with artificial sweeteners instead of avoiding them.