T cell reactivity to microbial antigens, collagen in RA after new meds
Etanercept is the new drug being used to treat rheumatoid arthritis and Crohn’s disease. I have always been concerned at the effects of blocking the action of TNF-gamma in the body. A more rational approach would be to use natural methods to block the production of TNF-gamma (anti-inflammatory diets, herbs, maintaining good insulin sensitivity, lowering the level of adipose tissue…). New research is suggesting that this new drug upregulates the immune system further, with the potential for even more autoimmunity–the reason the drug is used in the first place!!
Ann Rheum Dis — Abstracts: Berg et al. 60 (2): 133