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AED

Anti-Seizure Medications: Are You on Too Many?

May 25, 2015 by James Bogash

seizure medication use
Too many seizure meds may create problems

The mainstream approach to treating seizures is to use medications.  And it pretty much stops there.

You may get some cursory advice to exercise and watch your stress levels, but the reality is that many neurologists believe that nothing you can do will be as powerful as the anti-seizure medications.

When those medications don’t work at all (which is about 30% of the time) another medication is tried.  Most of this is guesswork.  There really is no science behind who will benefit from Drug A over Drug B.  Much of this is provider experiences—they go with what they know.  And they are more likely to try the new fancy drugs over the older ones that have decades of history.

When the list of drugs doesn’t work or doesn’t give adequate seizure control, another drug is added to the mix.  At this point, we’re completely out of the realm of double-blind placebo controlled studies and into guesswork.

Every anti-epileptic drug has a list of side effects.  Some minor, some life-debilitating.  And the more drugs you add in, the longer this list of side effects becomes.  And this still does not guarantee that the seizures will be controlled.

Poor controlled seizures are called refractory.  In this interesting study, researchers took 962 patients with drug refractory epilepsy and put them in a neurology ward to see what would happen if the number of medications they were on were reduced from an average of 4.24 down to a maximum of three AEDs during their stay in the ward.

Personally, I think 3 meds still sounds like an awful lot of foreign chemicals running through the brain.  I’d wonder how many of these patients were also trying natural approaches to seizures that have been shown to be effective like exercise, omega 3 fatty acids, vitamin D and diet.

Here’s what they found after these patients were followed up 6 months later:

  • After the tapering of the drugs, patients were on an average of 2.65 AEDs.
  • In 82.7% patients there was either a REDUCTION in seizure frequency or no change at all.

So basically, taking these patients off of some of their drugs led to no change or an actual improvement in seizure frequency.  Clearly there is something wrong with the way these patients were managed.  For me, this makes it clear that medications are not the only answer and can actually begin to create more problems than they solve.

If you suffer from seizures and the first medication that you take does not adequately control your seizures, it is clear that you can no longer rely on medications alone to help heal your brain.

While it is beyond the scope of this post to outline things that can be done to heal your brain, feel free to check out my Migraines and Epilepsy book by clicking here.

Filed Under: Seizures / Epilepsy Tagged With: AED, epilepsy, epilepsy medication, seizure medication, seizures / epilepsy

HAVE NEW SEIZURE DRUGS IMPROVED OUTCOMES?

February 17, 2012 by James Bogash

There is no doubt that some new, fancy and expensive anti-epileptic drugs (AEDs) have been developed and marketed.  It seems like neurologists actually prefer to use these new drugs over the older drugs that have had decades of use.

These new drugs can include sodium valproate (Depakote), lamotrigine (Lamictal), carbamazepine (Tegratol), levetiracetam (Keppra) or topiramate (Topamax).  Compare these with some of the older mainstays like phenytoin (Dilantin). 

These drugs are also being used increasingly to treat migraines and bipolar depression.

Read the entire article here

Filed Under: Migraine, Seizures / Epilepsy Tagged With: AED, epilepsy, migraines, seizures / epilepsy

Seizure, Epileptic Drugs Not Working? 4 Places to Start Healing Your Brain

February 1, 2012 by James Bogash

From the traditional medical approach to seizures and epilepsy, the foundation of the approach is anti-epileptic drug therapy (AED).  This foundation is added to by brain surgery or the use of a vagal nerve stimulator implanted in the chest.  That’s pretty much the armamentarium.  And pretty much disappointing when you look at just how effective these approaches are.  But they all leave one important thing out.

Read the entire article here

Filed Under: Migraine, Seizures / Epilepsy Tagged With: AED, diet, epilepsy, migraine, seizure

DRUG TREATMENT IN EPILEPSY AND MIGRAINES

January 22, 2012 by James Bogash

BRAIN DAMAGE OCCURS DESPITE SUCCESSFUL DRUG TREATMENT IN EPILEPSY AND MIGRAINES.  One of my continuing frustrations in our treatment of seizures (this includes true migraines) is that we view the treatement as successful if the seizures or migraines have stopped.  The reality is all we’ve done is dumbed down the brain cells’ ability to communicate with one another, but have not improved the health of the neurons.  In many cases it is quite the opposite.

This study adds weight to this idea in finding that treatment with one AED (Depakote) actually stopped the brain’s ability to recover from insult (plasticity) and promoted cognitive loss.

Read entire article here.

Filed Under: Migraine, Seizures / Epilepsy Tagged With: AED, epilepsy, migraine, seizures / epilepsy

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