Association between SSRIs and upper gastrointestinal bleeding

I must admit that this interaction never occurred to me, but it makes sense since platelets use serotonin for proper functioning. With the inhibition of the transporter that platelets use to pick up serotonin, this would affect platelet function. By themselves, the risk is not great, but add aspirin or NSAIDs into the mix, and the risk skyrockets.

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James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.