Resistance to Glucocorticoid Feedback in Obesity
Once again we see how important the adrenal glands are to our health. This study basically status that the adrenal cortex is shutting down in obese patients. The pituitary is trying to prod the adrenals to work but cannot get the adrenals to produce enough cortisol (and by inference I’m sure DHEA levels would also be low). Checking adrenal status is looking more and more to be an essential part of any workup on a patient with a multitude of chronic diseases.
JCEM — Abstracts: Jessop et al. 86 (9): 4109