Fasting Insulin, Triglycerides Predict Insulin Sensitivity – (05-14-01)



Fasting Insulin, Triglycerides Predict Insulin Sensitivity

This study evaluated 9 different factors that are related to insulin sensitivity and found that fasting insulin was one of the best ways to determine insulin sensitivity. This is good news because a fasting insulin is a much easier lab test than a oral glucose tolerance test. With the high prevalence of insulin resistance, I feel that fasting insulin should be a standard part of all blood workup.

Diabetes Care 2001;24:460-464 Log-transformed fasting insulin and fasting triglyceride values are the best of nine predictors of insulin sensitivity in the general population, according to a study conducted in New Zealand. Dr. Kirsten McAuley, of Otago University, in Dunedin, and associates compared the nine factors with results of euglycemic insulin clamping among 178 normoglycemic individuals deemed similar to the general population with respect to blood pressure, body mass index, and waist-to-hip ratio. According to the investigators’ report in the March issue of Diabetes Care, 42% of the sample met criteria for insulin resistance. They found that a fasting insulin of >12.2 mU/L was at least as good at predicting insulin resistance as homeostasis model assessment, insulin-to-glucose ratio, and the Bennett index. “Variables most strongly correlated with insulin sensitivity were fasting insulin, fasting triglycerides, aspartate aminotransferase.

James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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Category: Insulin
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