Double infection with H pylori and non-H pylori during acid-suppression
The co-infection of H pylori along with other bacteria during acid suppressive therapy is believed to contribute to the progression of atrophic gastritis, a condition where the portion of the stomach that produces stomach acid is destroyed. This article suggests a cycle of stomach problems treated with acid suppression that encourages bacterial growth. This growth then produces an increased inflammatory reaction against the stomach in an attempt to destroy the bacteria. The attack ultimately wears away the gastric antrum. I cannot stress how important stomach acid is to our health, and the casual nature with which acid suppression is prescribed and bought over the counter is frustrating. Any doctor willing to give acid suppressive therapy (with a few severe cases warranting its use) does not understand the physiology of the GI tract.
Synergy : Alimentary Pharmacology & Therapeutics 15 (8), 1163-1175