Advanced glycation end-products on PMN superoxide production – (12-17-01)



Advanced glycation end-products on PMN superoxide production

To put this in English, abnormally high levels of glucose in the blood stream will irreversibly damage proteins, a process called glycosylation. PMNs are white blood cells that help fight off bacterial infections; they do this by ingesting the bacteria and destroying them with a compound called superoxide.

Thus, this study connects the link between diabetics and increased susceptibility to bacterial infections. I would widen the net to dysglycemic patients as well; these patients will also have elevated glucose and insulin levels.

Synergy : European Journal of Clinical Investigation 31 (12), 1064-1069

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James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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