Tamoxifen may mean that later tumors are more aggressive
Let me understand here. We give tamoxifen to patients who have had breast cancer to prevent future recurrences. But, it turns out that, if that same patient on tamoxifen gets cancer in the other breast, that form of cancer will be much more aggressive. Too many times in medicine we try to manipulate hormones in the human body when we do not even truly know the whole picture. The outcomes for this can be dangerous with side effects worse than what we were trying to prevent in the first place.
J Natl Cancer Inst — Abstracts: Li et al. 93 (13): 1008