Relationship between total cholesterol/high-density lipoprotein cholesterol ratio, triglyceride/high-density lipoprotein cholesterol ratio, and high-density lipoprotein sub classes
While this study does not really add anything new (we already know that as triglycerides goes up due to insulin resistance then HDL will go down) it is a nice refresher to remind us that HDL has subclasses. The HDL2 subfraction is generally considered the most protective, and in this study, the authors found that, as triglyceride ratios changed for the worse, the HDL subclasses moved towards the “less friendly” type.