Percutaneous Coronary Intervention Results in Acute Increases in Oxidized Phospholipids and Lipoprotein(a)

While there is no question that, should I have a choice between PCI and open heart surgery, I would pick PCI anyday. But this procedure is done on many patients as a screening tool with chest pain. Many negative tests are done without thought to the long term consequences other than healing of the incision.

This study finds that there is a long term elevation of oxidized LDL (remember–LDL cannot damage our vessels until it gets damaged via oxidation) after PCI. This might be a willing trade off to the patient that avoided open heart surgery. But to the patient that was scoped to “rule out” obstructive lesions, this is not a good trade off. Maybe these findings will push a greater use of the non-invasive ultra fast CT, which does a nice job of ruling out cardiac involvement in patients with chest pain. Circulation — Abstracts: Tsimikas et al. 109 (25): 3164 –

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James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.