DHEA Inhibits VSMC Proliferation Independent of ARs and ERs
I know it’s a big, long, complicated title, but basically this study shows that DHEA has independent effects on reducing atherosclerosis. Although DHEA is produced by the adrenals and converted to testosterone and then estrogen, this is an example of a precurser hormone/molecule having physiologic effects. Pretty amazing. Now, I would not recommend running out and taking bottles of DHEA to lower risk of CVD. However, making sure that your adrenal glands are functioning optimally is very important to maintaining healthy, physiologicaly normal levels.
JCEM — Abstracts: Williams et al. 87 (1): 176