TNF in type 1 diabetics and glucose control and cardiovascular risk – (08-21-00)By
TNF in type 1 diabetics and glucose control and cardiovascular risk
This study points to TNF-alpha as a contributor to the damage done to the pancreas in Type I diabetes. Recall that TNF inhibitors are the new rheumatoid arthritis and now Crohn’s disease drugs. As research gets more and more specific, I truly believe that we will come to find really only a few abnormalities causing most of man’s chronic diseases. TNF-alpha is a perfect example.
Journal of Internal Medicine 248 (1), 67-76 The cytokine TNF-a reveals a complex relationship with diabetes. It is involved in beta-cell damage leading to type 1 diabetes, causes insulin resistance associated with obesity and is of influence in the formation of atherosclerotic vascular lesions. We were interested in the possible association of this cytokine with metabolic control and cardiovascular risk factors in patients with type 1 diabetes. Our data indicate that TNF-a plasma levels are increased in type 1 diabetes mellitus and reveal a significant association with metabolic long-term control parameters, HbA1c and fructosamine for glycaemic control, and HDL cholesterol for triglyceride metabolism, as well with lipid peroxidation.
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ABOUT THE AUTHOR
Since acquiring a passion for how the body works in chiropractic school, I have continued to indulge this desire by reading some 120 peer reviewed medical journals per month. I’m always learning more about how to help people avoid chronic diseases like diabetes, heart disease, dementia, osteoporosis, obesity and cancer, and pass along this information in my blog. There are currently almost 3,500 posts cataloged on almost every health topic imaginable. Click Here for more bio information