NSAIDs, First Occurrence of Heart Failure and Relapsing Heart Failure
I was not aware that NSAIDs will increase risk of recurrent attacks of heart failure, but it appears that this risk is quite substantial. This definitely fits the mold of the new selective COX-2 inhibitors increase risk of heart failure. Remember that we do not fully understand the physiology of most processes in the human body, and blocking one pathway artificially will inevitably produce downstream effects (usually harmful) due to the blocked pathway.