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LINK BETWEEN DENTAL HEALTH AND CARDIOVASCULAR RISK – (03-06-05)
Periodontal Microbiota and Carotid Intima-Media Thickness
This is by no means the first article linking dental health and cardiovascular risk. Whether it is a direct seeding of the bacteria into the bloodstream, an indirect up-regulation of the immune process fighting off the bacteria in the gums or a reflection of the overall health of the person has yet to be determined. What we do know is that dentists have the opportunity to intervene/identify patients at increased risk of CVD.
WHAT DO PARENTS THINK ABOUT INFLUENZA VACCINATION? – (03-06-05)
Parent Opinions about Universal Influenza Vaccination for Infants, Toddlers
It always seems interesting. Across the board, every survey ever looking at vaccination that I have come across shows more educated parents having lower rates of vaccination. Now why do you think that is?
IMPACT OF FLU VACCINATION ON SEASONAL MORTALITY – (03-28-05)
Impact of Flu Vaccination on Seasonal Mortality in the US Elderly Population
What does and doesn’t get lots of press never ceases to amaze me. This one did get some mild press for a day or so, but was quickly replaced by the info on vaccine shortages and where to get your vaccinations.
Huh? Okay, let me get this straight–a large review of the data shows vaccinations for the elderly do not save lives, but run out and get yours. Remember last year’s fear? Several elderly persons actually DIED standing in line for an intervention that was not going to have an impact on their own mortality. How ironic.
By the time next year’s “flu season” roles around, you can be the fear mongering and pressure to get vaccinated will be back full strength. How quickly we forget!
INFLAMMATION IS A MAJOR PLAYER IN OSTEOPOROSIS – (04-04-05)
Increased Prevalence of Celiac Disease and need for Routine Screening among patients with Osteoporosis
Remember that celiac disease is an allergy to the gluten portion in grains, principally wheat. This study found a direct correlation with the severity of celiac disease serum markers and the severity of osteoporosis. We already know that inflammation is a player in osteoporosis and that celiac disease up-regulates the immune system, so I guess the results of this study shouldn’t be a surprise.
The author suggests that the prevalence of patients with osteoporosis that have celiac disease is high enough to warrant routine screening.
EFFECTIVENESS OF INFLUENZA VACCINES IN HEALTHY CHILDREN – (04-04-05)
Assessment of the efficacy and effectiveness of influenza vaccines in healthy children: systematic review
To quote: “no studies assessed reductions in mortality, serious complications.” Well, isn’t that just wonderful considering how much of a push there is to get every child vaccinated with the flu vaccine.
Compare this with a recent review of the flu vaccine in the elderly used over the past 40 years or so with no reduction in mortality in those receiving the vaccine. And remember this next flu season–the push will be on again to get vaccinated and the scare tactics will be employed. We’ll forget these pesky little studies and line up like lemmings…
WHAT ARE THE PROBLEMS OF VIRAL INFECTIONS? – (05-01-05)
Glycyrrhizic acid alters Kaposi sarcoma–associated herpesvirus latency, triggering p53-mediated apoptosis in transformed B lymphocytes.
Wow. One of the problems with many viral infections is that they incorporate themselves into our own DNA so we can’t find them. This makes it difficult to find these contaminated cells and eradicate them.
This study suggests that glycyrrhizic acid (from licorice) may be able to help the body recognize these contaminated cells.
USE OF PROBIOTICS CAN CHANGE THE COMPOSITION OF THE BACTERIAL FLORA – (05-01-05)
Synergistic proinflammatory responses induced by polymicrobial colonization of epithelial surfaces
Before the title causes your eyes to glaze over, let me put this in a better light. This study confirms that bacteria present along the respiratory tract can amplify inflammation occurring in the airways.
This study specifically looked at Haemophilus influenzae and Streptococcus pneumoniae. So why is this interesting? Studies have shown that the use of probiotics such as lactobacillis can change the composition of the flora of the nasopharynx to less Strep and Staph and more Lactobaccillis. That can go in reverse–kill off normal flora with antibiotics, stick with processed foods present in todays’ foods (fermented foods such as yogurt and miso and tempeh contain probiotics, while Staph and Strep are pretty much found everywhere) so the good bacteria doesn’t get replaced, and Viola–instant source of increased airway inflammation.
VAGINAL VAULT INFECTION INCREASES RISK OF PRETERM BIRTH – (05-08-05)
Is a change in vaginal flora associated with an increased risk of preterm birth?
While clinicians are slow to recognize it, inflammation in the vaginal vault during pregnancy is not a good thing and increases the risk of miscarriage or preterm birth. So, chalk up another negative with our culture’s overuse of antibiotics. I still contend that the development of antibiotic resistant bacteria is the small problem–destruction of normal flora and the resultant negative health effects far outweigh the resistance issue.
Regardless, the use of probiotic douche would be a good idea to put in protective flora and reduce the risk of inflammation occurring in the vaginal vault from infection.
METABOLIC RISK FACTORS IN OBESE WOMEN – (05-08-05)
Metabolic risk factors in formerly obese women-effects of a pronounced weight loss by gastric band operation compared with weight loss by diet alone
Some interesting observations here. First, while no one should be surprised, I am NOT a fan of any type of gastric bypass. Mother Nature put it there for a reason. I’m sure that, when all the long term data are in, we will see much greater risks of chronic diseases in these patients due to malabsorption of any number of vitamins, minerals and phytonutrients.
That being said, the patients undergoing surgery lost more weight than those choosing the diet route, however, their insulin sensitivity was better than their dietary counterparts prior to surgery–suggesting that they may not have been as metabolically “bad off” as the diet group.
What I find VERY interesting was that, after surgery, this group of patients had elevated levels of TNF-apha, a marker of inflammation that begins a cascade of further inflammation in the body. Not a good sign, at all. Even more interestingly, this data were mentioned in the conclusion but no importance was given to this finding.
EFFECT OF A HIGH FIBER DIET VS A FIBER SUPPLEMENTED DIET ON CRP LEVEL – (11-05-07)
Effect of a High-Fiber Diet vs a Fiber-Supplemented Diet on C-Reactive Protein Level
Once it was realized that hsCRP as a marker of inflammation was related to a variety of chronic diseases, the hunt was on to find a drug to lower the level of CRP. While this approach is definitely not new and is more the norm, I’ll never understand the motivation when natural approaches already work. We already know that exercise and higher intakes of omega-3 fatty acids help to lower hsCRP, but now we can add fiber to the list.
And while the study looked at dietary as well as supplemental, the goal is to attain 30 g /day from diet alone; at this level of fiber it will come along bearing many other gifts in the form of phytonutrients.
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