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WHAT ARE PROBIOTIC ORGANISMS GOOD FOR? – (05-16-05)
Lactobacillus and bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles
Another article in a series of research trying to further elucidate exactly what probiotic organisms are good for what conditions. The difference in efficacy rates in various studies on conditions like inflammatory bowel disease, diverticulitis and irritable bowel syndrome may be because the specific strain may not have been the best choice for that study. As the specificity of probiotics for a given condition is identified, the therapeutic potential of this method of treatment will skyrocket.
CAN YOHURT CONTAINING PROBIOTICS HELP WITH ATOPIC DERMATISIS? – (11-05-07)
LKM512 yogurt consumption improves the intestinal environment and induces the T-helper type 1 cytokine in adult patients with intractable atopic dermatitis
While many may find it strange that what happens in the gut affects the skin, this is a pretty well accepted route of treatment for many skin disorders. I’ve found that, in infants, adding in probiotics can very rapidly turn around eczema. In adults, where the patterns are much more ingrained, the results are not usually as dramatic.
This study finds that consumption of a specifically designed yogurt that contains probiotics can help with atopic dermatitis scores in adults.
FACTORS CONTRIBUTING TO DYSPEPSIA – VIT C, STRESS – (10-29-07)
Initial Poor Quality of Life and New Onset Dyspepsia
Given that digestive problems are strongly related to lifestyle, the results of this study are not surprising. We know that probiotics help with H. pylori infection and it is likely that destruction of normal flora sets up the H. pylori infection in the first place. Lower levels of Vit C contribute. Stress greatly contributes. All these factors that can contribute to dyspepsia would also contribute to other health related problems.
That doesn’t even take into account what happens when we suppress gastric acid production with drugs. The bottom line is that dyspepsia needs to be addressed w/ lifestyle changes for the best results.
IS ANTIBIOTIC RESISTANCE A MAJOR HEALTH PROBLEM? – (10-29-07)
Prebiotics, Probiotics, and Synbiotics Affect Mineral Absorption, Bone Mineral Content, and Bone Structure
I’m really not making this stuff up. And despite thousands of articles relating probiotics to so many aspects of our health, how can we still think the major problem is antibiotic resistance? The number of patients affected by antibiotic resistance is paltry compared to the real number of patients affected by destruction of normal flora.
HOW EFFECTIVE IS THE TREATMENT OF PROBIOTICS? – (10-29-07)
Helicobacter pylori and Probiotics
Just in case you think the dangers of antibiotic overuse is limited to IBD risk (as if that wasn’t bad enough all on it’s own…) this article finds that addition of probiotics to treatment of H. pylori greatly increases its effectiveness and reduces side effects. Sounds great, right?
Here’s the real question–is the H. pylori present in the FIRST place because of destruction of the normal, protective flora years earlier by antibiotics? The answer is likely yes, and geezzz…what a boon for the drug companies, huh? One treatment increases the need for another, more expensive treatment later down the road!! What a gig!
PROBIOTIC EFFECTS ON INFLAMMATORY BOWEL DISEASE – (10-29-07)
Probiotic Effects on Inflammatory Bowel Disease
The relationship between probiotics and IBD is definite. The problem is that we don’t have all the details worked out just yet. What is very clear is that friendly bacteria is absolutely essential for healthy immune system development in the newborn and infant. Having them there early in life helps to set up a tolerance that forever helps balance the immune system.
If the balance is destroyed early, as is the case in any infant given antibiotics and not replaced w/ probiotics (I personally have yet to see a patient come into my office that has ever been recommended probiotics by their pediatrician), the risk for IBD goes up. The problem is that later in life, if the patient develops IBD, the strength of protectiveness of probiotics is not so clear cut.
The bottom line is that we HAVE to understand what antibiotics do to the long term trajectory of our health when given to our infants. To date, it is not and our greatest concern w/ antibiotic overuse remains resistance.
BENEFITS OF PROBIOTICS! – (08-13-07)
Lactobacillus reuteri (American Type Culture Collection Strain 55730) Versus Simethicone in the Treatment of Infantile Colic.
Infantile colic is an extremely difficult situation to deal with as a new parent. The reality is most likely that colic is multi-factorial and/or has separate categories. Growing pains, foods allergies (both direct and via nursing) and alterations in GI flora, and all these need to be addressed to fully impact this condition.
This article addresses the alterations in GI flora category, and finds rapid response in a whopping 95% of patients. Keep in mind that this is a pediatric journal and should be read by every practicing pediatrician. Maybe one day, if pediatricians ever actually realize the benefits of probiotics, we will see more deliberation before using antibiotics except when absolutely necessary.
DESTRUCTION OF NORMAL FLORA THROUGH USE OF ANTIBIOTICS – (07-23-07)
Gut-associated bacterial microbiota in paediatric patients with inflammatory bowel disease
This study identified alterations in the gut bacteria of pediatric patients w/ IBD (Crohn’s, Ulcerative colitis), both increases in pathogenic bacteria and reductions in protective.
The bottom line is that destruction of normal flora through the indiscriminate use of antibiotics will have a much further reaching consequence then what most prescribing pediatricians will ever be aware of.
BENEFITS OF THE USE OF PROBIOTICS – (07-09-07)
Daily Intake of Heat-Killed L. plantarum L-137 Augments Acquired Immunity in Health Adults
The benefits of probiotics are derived not only from their living functions, but from their ability to modulate our immune system beginning from the gut. A large chunk of the control of our immune system starts in the gut (as much as 2/3 depending on who you talk to) and this then sends out the signal to the rest of our immune system.
It’s one of the reasons why persons w/ celiac disease (allergy to gluten in grains) have a higher overall mortality rate if they continue to eat gluten. This activates the immune system, leading to an overall increase in systemic inflammation. Systemic inflammation slows beats up our bodies, increasing the risk of chronic diseases.
USE OF PROBIOTICS REDUCES SEVERITY OF COMMON COLD – (07-09-07)
Probiotic bacteria reduced duration and severity of common cold
I had a mom bring in her 1 yr old baby that had a history of reflux (meds at 3 months) and now recurrent ear infections. Figuring out what was wrong was not difficult (pretty clear cut allergy to dairy), but of issue was the multiple courses of antibiotics she had been on. Recently, she had taken her daughter to urgent care, and the physician recommended she give her daughter probiotics. A little surprising, but good nonetheless. Her pediatrician, however, told her later there was no evidence on probiotics. I told her she needs to find a pediatrician who has cracked a medical journal in the past decade.
The bottom line is that these commensal bacteria are supposed to be there. The benefits of having them there are too many to mention. I firmly believe that this is the most devasting impact of innapropriate antibiotic use.
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