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DAIRY INTAKE LEADS TO FUTURE RISK OF PARKINSON’S DISEASE – (04-25-05)
Consumption of milk and calcium in midlife and the future risk of Parkinson
I’ve said it before, and I will say it again (and again, and again…) that I think the idea that cow’s milk “does a body good” is one of the most successful marketing campaigns based on little to no evidence ever exposed to the American public. Good luck finding any articles not sponsored by the dairy industry that show a strong beneficial effect on dairy products for any condition.
Conversely, dairy intake has been linked to food allergy, ear infections, osteoporosis (or at least no protection from), Type 1 diabetes and now add Parkinson’s to the list. Ironically, although this showed a 2.3 fold increase (quite a large increase) and it was in a major neurology journal, not a PEEP from the media. Compare this to a 3-lb decrease in body weight over 6 months with dairy intake (and no-one just body fat–just weight) and you would think the Holy Grail for America’s weight problem was found.
COST OF SIDE EFFECTS OF LIFESTYLE INTERVENTION – (05-01-05)
The Cost-Effectiveness of Lifestyle Modification or Metformin in Preventing Type 2 Diabetes
Ouch. Lifestyle intervention: $1100. Metformin: $31,300. These costs take into account the intervention as well as cost of side effects of the intervention. Would seem kind of like a no brainer for the insurance companies, but they still do not pay well or consistently for lifestyle/therapeutic lifestyle changes (TLC).
IMPROVEMENT IN METABOLIC RISK FACTORS FOR CVD – (05-08-05)
Effect of orlistat on cardiovascular disease risk in obese adults
Just so you know–it wasn’t me that designated April/May as “beat up the pharmaceuticals for obesity” months.
This study found improvements in several metabolic risk factors for CVD, but not enough to lower 10-year risk assessment. Interestingly, although the patients on orlistat had lower total cholesterol, none reduced their cholesterol lowering meds. I can practically guarantee that lifestyle changes geared towards a healthy body composition will definitely lower a patient’s need for cholesterol lowering drugs.
METHODS OF LOSING METHOD TO TREAT OBESITY – (05-08-05)
Meta-Analysis: Pharmacologic Treatment of Obesity
Speaking of less-than-preferred methods of losing weight…There is much debate about whether these drugs are actually even better than placebo, but lets say they are. Taking sibutrimine alone, the additional weight lost in a year over placebo was just shy of 10 pounds. The cost? Probably close to $1000. That’s about $100/per pound. Not to mention any costs associated with physician visits and costs associated with any interventions needed to deal with any serious adverse effects that occur. 10 pounds in a year.
On a strickly calories in/calories out model of weight loss, that could be achieved by cutting caloric intake by 57 calories per day. That’s like one less Snickers bar per WEEK. Why anyone would even consider these drugs is beyond me. They have side effects that, in some cases have been lethal, the cost ain’t exactly cheap, and they don’t teach anything about fixing the real problem which is lifestyle. Also, not surprisingly, any studies of these pharmaceutical approaches to weight loss focus on WEIGHT–not body composition. I would put some money on the fact that a large chunk of weight loss is coming out of the muscle mass.
METABOLIC RISK FACTORS IN OBESE WOMEN – (05-08-05)
Metabolic risk factors in formerly obese women-effects of a pronounced weight loss by gastric band operation compared with weight loss by diet alone
Some interesting observations here. First, while no one should be surprised, I am NOT a fan of any type of gastric bypass. Mother Nature put it there for a reason. I’m sure that, when all the long term data are in, we will see much greater risks of chronic diseases in these patients due to malabsorption of any number of vitamins, minerals and phytonutrients.
That being said, the patients undergoing surgery lost more weight than those choosing the diet route, however, their insulin sensitivity was better than their dietary counterparts prior to surgery–suggesting that they may not have been as metabolically “bad off” as the diet group.
What I find VERY interesting was that, after surgery, this group of patients had elevated levels of TNF-apha, a marker of inflammation that begins a cascade of further inflammation in the body. Not a good sign, at all. Even more interestingly, this data were mentioned in the conclusion but no importance was given to this finding.
WHAT ARE THE SIDE EFFECTS OF METFORMIN? – (05-16-05)
Effect of Metformin and Intensive Lifestyle Intervention on the Metabolic Syndrome
I’ve always said that, while metformin does indeed reduced insulin resistance, I strongly advocate lifestyle changes first and foremost. Metformin reduced incidence by 17%, lifestyle by a whopping 41%. So, lifestyle changes are much more effective and metformin carries significant risks of side effects. The side effects of lifestyle change? Lowered rates of diabetes, CVD, osteoporosis, osteoarthritis, cancer….
HOW DETRIMENTAL IS INSULIN RESISTANCE TO OUR HEALTH? – (05-23-05)
Rise in Insulin Resistance is Associated With Escalated Telomere Attrition
Sometimes I get sick of hearing myself rant and rave about insulin resistance and how detrimental it is to our health, so I can imagine how my patients feel! But this study says it all. Recall that telomeres shortened as our cells age. They are essentially our cells’ hourglass on life; shorter=less life. Insulin resistance shortens telomeres. Period.
Can anyone explain to me why I have to keep explaining insulin resistance to seemingly everyone in my office and in the community that I have contact with? Why is this condition so incredibly ignored? It is the single most devastating physiological imbalance occurring in Westernized countries and it is virtually ignored!! (Oops…I’m ranting again…)
SUCCESSFUL LONG TERM WEIGHT LOSS NEEDS ROUTINE EXERCISE – (12-03-07)
Long-term weight losses associated with prescription of higher physical activity goals. Are higher levels of physical activity protective against weight regain?
Not to burst anyone’s bubble, but we’re finding a much harder job of shutting the barn door after all the animals have gotten out. This article finds that very few people beginning an aggressive workout routine remained complaint w/ that routine, but these were the only ones that had successful long term weight loss.
Two things to consider here. First, obesity, just like any other chronic disease, is easier prevented then treated. Consider the overweight 10 year old. They actually have more fat cells, and as they lose weight, these cells merely shrink but do not go away. They will forever be fighting their weight. Second, maybe aggressive activity may not have been the answer to their exercise dilemma. Stay tuned to these Updates for further information on why many may not achieve balanced body composition with aerobic type exercises.
IMPROVE INSULIN SENSITIVITY BEFORE GOING FOR INFERTILITY TREATMENT – (12-03-07)
Insulin Resistance Increases the Risk of Spontaneous Abortion after Assisted Reproduction Technology Treatment
“Patients with IR should be advised to improve their insulin sensitivity through lifestyle change or medical intervention before infertility treatment to reduce their risk of spontaneous abortion.” HAH!! Like that would ever happen!! Why change anything when IVF is available on every corner?
The bottom line is that we cannot and should not ever try to cheat Mother Nature. There will always be a price to be paid. The rapid increase in IVF pregnancies will come with a price to society–as unhealthy mothers give birth to predisposed babies who are raised in the same unhealthy manner we will start seeing chronic diseases begin earlier and earlier in age
DRINK CAMEL MILK TO PREVENT DIABETES – (12-03-07)
Zero prevalence of diabetes in camel milk consuming Raica community of north-west Rajasthan, India
Can’t say I’ve seen it in the local aisles of Safeway, but there is definitely something to be said for people eating the foods that their ancestors ate.
And in this particular instance, ZERO percent is kind of hard to argue with, especially when compared to comparable non-milk drinkers at 5.5%. Almost wants to make you run out and buy your own camel. Not sure how my HOA would react to that one…
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