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Bldg 7, Ste 135
Mesa, AZ 85210
(480) 839-2273

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Diabetes and obesity tips

Current Gallbladder Pain – Blame Your Younger Years

Sure-you remember fondly back on your youth, high school and college days.  I remember doing things as a child that, if I saw my son doing them, I would think he’s out of his mind and I was doing a poor job as a father.  Then there’s the near-permanent frontal lobe damage so many seem to accomplish in college (which, by the way, is not true–the brain remains plastic long into our adult years).  But did you ever think about about what damage is being done to our gallbladders?

Given the state of medicine today, one would think that the gallbladder is near-vestigial and can be taken out on a whim with nary a price to pay. 

First, we need to understand some of the basic functions of the gallbladder.  The absolute most important job of the gallbladder is to store the bile that is constantly produced in the liver and release bile in response to the hormone CCK in response to a fatty meal.  The bile released then helps to emulsify and absorb the fat and fat soluble nutrients of our meal.

So what happens after a cholecystectomy (gall bladder removal)?  There are several negative consequences.

  1. Most common is diarrhea.  This is because there is now unabsorbed fat in the intestinal tract (no bile to help with the absorption) which contributes to the osmotic diarrhea commonly seen.  Luckily, supplements containing bile acids can very successfully relieve the diarrhea.
  2. Fat soluble nutrient absorption problems.  This includes the fat soluble vitamins A, D, E and K, but also fat soluble phytonutrients like lycopene (the red pigment in tomatoes that are known to protect the prostate and heart) and a long list of others.  Supplementation with certain vitamins is essential.
  3. Increased risk of colorectal cancer.  The reasoning is not quite worked out, but it likely has to do with the constant slow release of bile acids from the liver that are no longer stored.  Because they aren’t stored and released to bind up with fats as needed, they are free to float down into the intestinal tract and create problems among cells that are not designed to handle the acids. Eating certain foods regularly may help bind up the bile acids and lower the risk of harm.

These little tidbits are rarely shared with patients prior to their surgical removals (which, by the way, is actually required–it’s called informed consent and is grounds for malpractice).  All too often, even severe gallbladder attacks are NOT grounds for gallbladder removal, despite popular opinion.  Recent studies suggest less than a third of patients with severe symptoms will continue to have problems.  This means that more mild symptoms should not even initiate the conversation.

Of course, the real answer is not damaging our gallbladder in the first place.  And this, while trying to avoid sounding like a broken record, is almost always a result of being prediabetic.  I’ve always told patients that gallbladder problems can occur decades before someone actually becomes diabetic.  So, of course, fixing the gallbladder has everything to do with pulling back from a pro-diabetic lifestyle.

This particular article gives us some insight into just how early this process starts.  Researchers found that obese preadolescents actually began to have problems with gallbladder motility long before they became an adult. 

I do not need to stress to anyone just the life altering importance of raising our children with good lifestyle habits and maintaining an ideal body composition.  If your child is NOT in this category, you need to understand fully that the damage to their delicate bodies has already begun.

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CHARACTERISTICS OF METABOLIC SYNDROME – (02-21-05)

Effects of rosuvastatinatorvastatinsimvastatin, and pravastatin on atherogenic dyslipidemia in patients with characteristics of the metabolic syndrome

Okay.  A couple problems here.  This study reviewed several statin drugs to determine which one lowered lipids better in patients with metabolic syndrome.  You know metabolic syndrome the condition where high INSULIN levels increase lipids.

So here’s my analogy:  Your house is on fire and the smoke detector is going off.  We take a baseball bat, hammer and the wrong end of a screwdriver and beat on the smoke detector to see which one breaks the detector into the smallest pieces.  Forget the fire–that’s not important.

And, just to be consistent with this study for my analogy, Astra Zeneca, the manufacturer of the hammer (which was found to be the most effective), paid for the study.  Suspicious?  And does anyone wonder why they didn’t check corresponding insulin levels?

Read entire article here

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ASSOCIATION BETWEEN DIETARY ARGININE AND C-REACTIVE PROTEIN – (03-28-05)

Association between dietary arginine and C-reactive protein

We really can’t let information like this get out.  That would totally ruin the drug company’s hopes for the next blockbuster drug when they finally figure out how to lower CRP pharmaceutically.  Of course, the fact that managing insulin resistance, exercise and fish oils bring down CRP levels has not stopped them.

But, mark my words–the second it is confirmed that a drug lowers CRP levels (there are currently several trials of the potential for statins to lower CRP), there will be advertisements all over telling patients to have their CRP levels checked…  We saw the same push with irritable bowel syndrome once the new anti-motility drugs were released.

Read entire article here

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Deadly Class of Diabetic Drugs

In general, people take medications for condition A because condition A is dangerous, with the thought process being the drug will protect the patient from bad outcomes.  The patient lives in happy oblivion, the drug companies make money and the doctors think they’re doing a good job.  Truly a house of cards.

All too often, the drugs being given to these patients actually SHORTENS lifespan.  Granted, these patients will die with better numbers, and everyone at the funeral will look at each other and say, “We don’t know how it happened–her numbers were under control.”  They are NEVER “under control” when drugs are used.  Never forget that.  It is the biggest fallacy mainstream medicine has ever produced.

Certainly statin drugs fall under this category.  Many blood pressure drugs as well.  This particular article again looks at the sulfonylurea class of drugs used to treat diabetes.  Glipizide (Glucotrol), Glyburide (Micronase), glimepiride (Amaryl).  Before we go over the specifics of this article, you need to understand the history of the sulfonylurea side effects.

  1. As early as 2001, reports were demonstrating increased mortality rates in sulfonylurea users.
  2. In 2005, researchers began to see that sulfonylureas actually caused damage to the insulin secreting beta cells of the pancreas.
  3. In 2006, sulfonylureas were shown to double the risk of dying in diabetics, with higher dosages further increasing the risk.
  4. In 2008, researchers delved a little deeper to identify how sulfonylureas destroy beta cells.
  5. In May of 2009, the well is dug deeper on how sulfonylureas destroy the beta cells.
  6. In August of 2009, researchers showed that those patients on sulfonylureas were sufferring greater rates of heart disease.

 Now that you can begin to understand how long this class of drug has been a concern, one should begin to wonder why it is even on the market.  Which brings us back to this current article.  Instead of spending valuable research money on other things, we spend money on finding out which member of this class of drugs is going to be the least worst. 

How does that go at your doctor’s office?  “Hey doc..can you give me the drug for my diabetes that’s slightly less likely to kill me before it saves me?” 

As always, scrap the drugs and manage diabetes the ONLY way it should be.  With lifestyle.

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DRINK RED WINE TO LOWER INSULIN RESISTANCE – (03-28-05)

Red wine consumption improves insulin resistance but not endothelial function in type 2 diabetic patients

I just recently ran blood-work on a patient that drinks red wine on a consistent basis and she has a beautiful triglyceride/HDL ratio.  My gut feeling is that the red wine she drinks is a factor in her lowered insulin resistance.

The amount consumed daily in this study was 360 ml, which is about a have bottle of wine per day.

Read entire article here

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12 Days to Diabetes

The human body is remarkable in its resilience, but when our physiology heads south, it does it in a bad way, taking every system with it.  Clearly, diabetes is the most powerful and important thing that human physiology rails against.  Nothing is as important as living an anti-diabetic lifestyle.

Do this and your risk of all chronic diseases will fall.  It’s that simple.  There is not an “anti-heart disease diet” or an “anti-cancer” diet–they are all “anti-diabetic” diets.  Our bodies are very well adapted for surviving well under famine conditions.  However, drop our physiologies into a world loaded with low value calories and we go to hell in a handbasket.  But just how fast can this occur?

This particular study gives us some insight into just how quick we can ruin good health.  Researchers took healthy volunteers and added a high-calorie diet, sedentary lifestyle, and administration of steroids for 12 days.  Twelve days.  Just under two weeks (but thankfully, less than the time of a typical vacation or all you can eat cruise…).

The subjects in the study had altered glucose responses and altered incretin responses to these changes.  So what does this really mean?  It means that healthy subjects, without any risk factors for diabetes, can be pushed strongly towards diabetes in a very short time frame.  This is NOT GENETICS, this is lifestyle.  Period.

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BALANCE OF VISCERAL VS SUBCUTANEOUS FAT – (04-04-05)

Differential Responses of Visceral and Subcutaneous Fat Depots to Nutrients

Wow.  What an insightful approach.  Basically, visceral (bad) and subcutaneous fat have a different response in the level of release of hormones after a glucose load.  The hormones derived from adipose tissue (resistin, leptin, adinopectin, PAI-1) generally contribute to insulin resistance and obesity.  More is released by visceral fat after feeding.

So the authors have planted a seed–might checking blood levels in non-fasting states give us more insight into the balance of visceral vs subcutaneous fat?  Interesting, huh?

Read entire article here

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Heartburn or Prediabetes, Which Leads to Esophageal Cancer?

There are times when it seems like every other patient coming into my office is on some type of acid blocker drug to treat their ulcer or heartburn.  Most have the mistaken belief that they make too much stomach acid.  Consider this: stress lowers stomach acid production and stomach acid production drops as we get older.  With these two factors alone, do you think there is anyone who makes too MUCH stomach acid these days?

The easy answer is no.  However, if someone has a bleeding ulcer, blocking the acid production will likely save his or her life.  Every other case is likely to do much more harm than good.  The list of problems associated with acid blocking drugs is quite long.  This should come as no surprise given that stomach acid is absolutely essential for a large number of critical processes in the human body (digestion, activation of other enzymes, sterilization of bacteria, activation of the pancreas, absorption of certain nutrients, activation of anti-cancer compounds, etc…).

The list includes:

The recommendation for acid blocker drugs in many times goes beyond symptom relief and more into the mistaken belief that acid blocking drugs will prevent the progression to Barrett’s esophagus and then to esophageal cancer.  As you can see from the study above, the opposite is true.  These drugs may actually increase the risk for the condition many doctors are trying to prevent.

This particular article adds weight to this, suggesting that prediabetes is as great of a risk factor, if not greater, for the development of Barrett’s esophagus than is reflux.  In some cases quadrupling the risk.  This means that the approach to managing any type of gastric issue, whether reflux, ulcer or gastritis needs to involve the whole spectrum of lifestyle changes to head the patient away from diabetes.  Shocking to hear me say this, but true.

The other thing to consider is that, most often, patients with heartburn actually make too LITTLE stomach acid.  Supporting digestion, using probiotics and improving the diet can go av very long way towards getting rid of reflux for good.

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MECHANISM UNDERLYING OXIDATIVE STRESS – 05-01-05)

Mechanism underlying oxidative stress-mediated lipotoxicity

In a nutshell, the researchers in this study found that elevated triglycerides (as would be found in insulin resistance) get sucked up into the macrophages (a type of white blood cells), and once there, started to destroy the mitochondria of the cell resulting in cell death.  The death of a macrophage in the bloodstream can lead to the production of foam cells and subsequent plague in the arteries.

Interestingly, vit C, NAC and resveratrol protected the macrophages from this death.  So, to extrapolate into a living, breathing human, antioxidants protect the cells that produce plaquing in the arteries, resulting in less plaque.

Read entire article here

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HOW GOOD IS TO CONSUME DARK CHOCOLATE? – (04-25-05)

Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure

Need I say more?  Remember, though, that this is dark chocolate, NOT milk chocolate with all it’s added sugar.

Read entire article here

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