Anger Makes Your Cells Age Faster
Anger is clearly one of the most misused emotions. Certainly it plays a role in good emotional health when properly directed and channeled. But how many of us are successful at managing our anger this way? I see some many patients who lives are ruled by anger–most often directed at people who could care less and are probably not even aware of anger being directed at them. Certainly this application of anger is pathological in our relationships, but what about our health? You bet!
I have discussed telomeres at length in prior posts. Suffice it to say that they are the wicks of our lives…the shorter they are, the less time you have to live. Protect them at all costs.
So what does this have to do with anger? You guessed it–anger shortens telomeres.
In this particular article, researchers looked at cynically hostile people. Cynical hostility is defined as a personality trait characterised by general cynicism and mistrust in interpersonal relationships. Those expressing cynical hostility had shorted telomeres and higher levels of the enzyme telomerase that shortens telomere length.
For those of you who would brush off the results of this study (mainly because you know it describes you perfectly), understand that this is far from the only study linking anger and hostility to health problems. The connection is clear and real.
With this in mind, the question you HAVE to ask yourself….Is this reason I’m angry worth dying over????
BENEFITS OF CALORIE RESTRICTION IS LOWERING OF INSULIN LEVELS – (04-25-05)
Undernutrition w/o malnutrition as a protective factor to prevent DNA damage in the elderly
Despite the infomercials, emails and all the anti-aging miracles you get in the mail, the only thing that has consistently shown to extend lifespan in mammals in calorie restriction without nutrient restriction.
This is an interesting study in that it is done in healthy elderly patients. With a mild caloric restriction of 10-20%, the research found less DNA damage in the patient’s white blood cells. Most of the research seems to suggest that much of the benefit of calorie restriction has something to do with lowering insulin levels.
DECLINE IN SKELETAL MUSCLE MITOCHONDRIAL FUNCTION – (05-16-05)
Decline in skeletal muscle mitochondrial function with aging in humans
While we know that skeletal muscle declines with age (a condition referred to as sarcopenia) but the exact mechanism has not been pinned down. Less building of muscle? Increased breakdown?
This article points to my particular “demise of Western civilization as we know it” reason which is oxidative stress and mitochondrial dysfunction. While my wife does not enjoy my deep discussions of mitochondria oxidative phosphorylation over dinner, when my “mitochondrial dysfunction as the root of all evil” book hits the shelves as a bestseller I’ll be able to stick my tongue out at her…
CALORIE RESTRICTION – A POWERFUL MECHANISM – (10-29-07)
Neuroprotective potential of the Bahadori leanness program: A “mini-fast with exercise” strategy
This concept continues to intrigue me. Regular readers of Updates will know that I feel that the increase in mitochondrial number and function with caloric restriction w/o nutrient restriction is a potentially very powerful tool but hard to get compliance. There have been variations on this theme, such as alternate day calorie restriction.
This concept looks at calorie restriction w/in the context of an aggressive aerobic workout in the middle of a fast, with appropriate supplementation to support fat oxidation, to provide both lean body composition as well as neuroprotection. There is quite a bit of supporting research to go along with this concept, making it a strong contender for a protective lifestyle against most chronic diseases.
CONCEPT OF CALORIE RESTRICTION WITHOUT NUTRIENT RESTRICTION – (09-17-07)
Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma
The concept of calorie restriction without nutrient restriction really intrigues me. While I have not used it clinically, the research supporting this type of approach is rapidly growing, and almost everything I’ve read is positive.
The problem with calorie restriction is that most patients would not be willing to partake in this as a lifestyle choice. The drug companies are trying to find out how to mimic it with a pharmaceutical compound and the researchers are trying to figure out how to make a CR approach more appealing to the masses. The idea of restricting calories every other day is definitely do-able.
Initial research suggests that calorie restriction increases both the efficiency and number of mitochondria. Basically, the body becomes very effective in utilizing all calories that come into the body and does this by making more and “stronger” mitochondria.
In this particular study, researchers found that alternate day CR in 10 obese patients with asthma had positive effects as soon as 2 weeks. Pretty strong findings for such a safe approach.
CALORIE RESTRICTION HAS A POSITIVE EFFECT ON THE MITOCHONDRIA FUNCTION – (08-13-07)
Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging.
Calorie restriction has a definite, positive effect on the functioning of mitochondria.
This study adds to our understanding, and finds that CR also helps to increase the efficiency of the enzymes in the cell well of neurons that recycle antioxidants such as CoQ10 and Vit E. CR or alternate day CR needs to be a tool in the treatment box of neurodegenerative disorders such as epilepsy, Alzheimer’s and Parkinsons.
EATING ENERGY DENSE FOODS LEADS TO…
Ok…so the answer to this one may be a little self-explanatory. But it is such an important concept that it bears repeating. Our bodies respond much, much better to a low calorie, high phytonutrient diet. As I’ve mentioned before, this means that your 1200 calories per day comes from broccoli and not a Value Meal.
In society today, we seem to be addicted to energy dense foods. Certainly energy dense foods with high phytonutrient value are ok sometimes and in moderation. Think chocolate, nuts, olive oil and guacamole.
But the energy dense foods we seem to gravitate towards here in the US are the energy dense, low phytonutrient foods. Think Big Mac, milkshakes, ice cream, cake, extra whip frappuccino, soda and candy bars. There is no good rationale for us to be eating these types of foods. Our bodies respond very poorly to them and chronic disease is clearly the result.
This particular study lends weight to what you probably already knew. Eating energy dense foods dulls the body’s response to these foods, thus resulting in greater intake of more energy dense foods. Basically a downward spiral into obesity, diabetes and cancer.
The bottom line is that you should evaluate every morsel that is going to cross your lips. Consider both the energy density (high calorie or low calorie) and the phytonutrient value (broccoli vs french fries). Eat high calorie foods with high phytonutrient value in moderation. Eat low calorie, high phytonutrient foods with abandon (no one ever became obese eating broccoli and cauliflower). Absolutely avoid high energy density, low phytonutrient value foods except in the rarest of circumstances.
As a side note, you should also skip low calorie, low phytonutrient foods. Think diet soda. Mother Nature does not make any foods that fit into this category that I am aware of. They are almost always chemically achieved.
CALORIE RESTRICTION LOWERS THE RISK OF CHRONIC DISEASES – (07-30-07)
Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk
I would be happy going on record that I’ve never been a fan of the high-protein type diets, feeling that short term weight loss is traded for long term health. These types of diets will kill you if you stay on them long enough.
That being said, I’m really sorry to find a study supporting my position. But even more importantly, this is yet another study finding that calorie restriction lowers the risk of chronic disease. It is really at the point now that we can no longer deny that our culture’s obsession with larger portion sizes and the accompanying additional calories w/o the additional nutrition are killing us more rapidly then we could imagine.
ARE OUR CALORIES KILLING US? – (07-30-07)
Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates
Regular readers of updates know that I consider mitochondrial dysfunction as the root of all evil when it comes to chronic diseases. Anything we can do to protect the mitochondria will have a positive effect on health and longevity. It has been well established that calorie restriction is the ONLY intervention known to extend lifespan in mammals. This means that your 1200 calories / day comes from broccoli, not a Big Mac and super-sized fries. It is believed that one of the mechanisms that CR works is by improving the number and efficiency of the mitochondria.
This study adds to that, finding that CR in primates leads to reduced immune senescence, or shutting down of the immune system with age. A healthier immune system means persistant cancer surveilance and retained ability to fight off infectious diseases. Definitely a good thing. The research has also played around with the concept of alternate day CR as well as short term fasting coupled with aerobic exercise. Some researchers actually disagree with the concept of CR extending lifespan. Rather, they believe that increased caloric intake SHORTENS a normal lifespan… In other words, our calories are killing us.
Brain Damaged From Migraines or Seizures? Try These 6 Tips
In my experience, many migraine or seizure sufferers do not fully understand that, even when headaches or seizures are not occurring, there is brain damage occurring. Luckily, there are many proven ways to help protect your brain from these dangerous conditions.
