Iron may worsening inflammatory bowel disease – (07-07-00)



Iron may worsening inflammatory bowel disease

This becomes a catch-22 because many patients with IBD are enemic. It may be possible to use a higher quality iron supplement so absorption is better and no iron will make it into the large intestine.

European Journal of Clinical Investigation 30 (6), 505-510 Iron supplements may increase disease activity in inflammatory bowel disease through the production of the hydroxyl radical. Oral as well as rectal administration of iron resulted in increased pro-inflammatory cytokine production in IL-10-/- mice. We conclude that dietary or topical administered iron increases pro-inflammatory cytokine production in the colon of IL10-/- mice. No significant increase of histological intestinal inflammation was observed.

James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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Category: Inflammatory Bowel Disease
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