Reduced susceptibility to ischemic brain injury in COX-2-deficient mice – (02-02-01)



Reduced susceptibility to ischemic brain injury in COX-2-deficient mice

Selective COX-2 inhibitors such as Celebrex and Vioxx are the new rage in treatment of joint pain. There have been some additional findings in research studies, suggesting a protective effect on colon cancer. This study, although done in mice, suggests a reduction in the damage sustained during an ischemic stroke when COX-2 is not even present. Don’t let this convince you to run out and start taking Celebrex; instead, consider this as yet additional evidence that inflammation is a contributing factor to most diseases and you would do well to maintain a lifestyle that reduces inflammation.

PNAS — Abstracts: Iadecola et al. 98 (3): 1294

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James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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